1268262-15-2Relevant academic research and scientific papers
A Reagent for Amine-Directed Conjugation to IgG1 Antibodies
M?rcher, Anders,Palmfeldt, Johan,Nisavic, Marija,Gothelf, Kurt V.
, p. 6539 - 6544 (2021)
Functionalized antibodies are an indispensable resource for diagnosis, therapy and as a research tool for chemical biology. However, simpler and better methodologies are often required to improve the labeling of antibodies in terms of selectivity and scal
Protein kinase affinity reagents based on a 5-aminoindazole scaffold
Krishnamurty, Ratika,Brock, Amanda M.,Maly, Dustin J.
supporting information; experimental part, p. 550 - 554 (2011/02/27)
Affinity reagents that target protein kinases are powerful tools for signal transduction research. Here, we describe a general set of kinase ligands based on a 5-aminoindazole scaffold. This scaffold can readily be derivatized with diverse binding elements and immobilized analogs allow selective enrichment of protein kinases from complex mixtures.
