1268482-50-3

Upstream product

• 108-30-5 succinic acid anhydride 
• 174158-56-6 N-(2-{{2-[2-(1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-acetylamino]-ethyl}-[2-(2,2,2-trifluoro-acetylamino)-ethyl]-amino}-ethyl)-2,2,2-trifluoro-acetamide 

Relevant academic research and scientific papers

Synthesis of modified siRNA bearing C-5 polyamine-substituted pyrimidine nucleoside in their 3′-overhang regions and its RNAi activity

Short interfering RNA (siRNA) induces specific gene silencing by the RNA interference (RNAi) pathway. Nucleosides in the 3′-overhang regions of siRNAs were replaced with 5-bis(aminoethyl)aminoethylcarbamoylmethyl-2′- deoxyuridine or thymidine. siRNA beari