1268830-48-3Relevant academic research and scientific papers
Construction of substituted imidazoles from aryl methyl ketones and benzylamines via N-heterocyclic carbene-catalysis
Alanthadka, Anitha,Elango, Sankari Devi,Thangavel, Pavithra,Subbiah, Nagarajan,Vellaisamy, Sridharan,Chockalingam, Uma Maheswari
, p. 26 - 31 (2019/03/26)
A novel synthetic strategy for the construction of substituted imidazoles from acetophenones and benzylamines via N-heterocyclic carbene (NHC) - catalysis was reported. This reaction can be performed under solvent-free condition without pre-functionalization of substrates. Various substituted acetophenones and benzylamines were converted to its corresponding imidazoles with good to excellent yields.
Commercial Supported Gold Nanoparticles Catalyzed Alkyne Hydroamination and Indole Synthesis
Liang, Shengzong,Hammond, Luisa,Xu, Bo,Hammond, Gerald B.
supporting information, p. 3313 - 3318 (2016/10/21)
Commercial gold nanoparticles supported on titanium dioxide (TiO2) were found to be a highly efficient catalyst for alkyne hydroamination. Terminal alkynes could easily undergo intermolecular hydroamination with low catalyst loadings (0.2 mol% Au) under solvent-free conditions. Indoles were efficiently synthesized using microwave heating through intramolecular hydroamination. (Figure presented.).
Rhodium(III)-catalyzed hydroamination of aromatic terminal alkynes with anilines
Kumaran, Elumalai,Leong, Weng Kee
experimental part, p. 1068 - 1072 (2012/04/04)
The dinuclear Rh(III) species [Cp*RhCl2]2 catalyzes the hydroamination reaction between an aromatic terminal alkyne (ArCCH) and an aniline (Ar′NH2), in the presence of a salt additive, to afford the ketimine Ar′N=C(Me)(Ar). A reaction pathway has been proposed on the basis of experimental and computational studies.
Palladium-catalyzed aerobic oxidative cyclization of N-aryl imines: Indole synthesis from anilines and ketones
Wei, Ye,Deb, Indubhusan,Yoshikai, Naohiko
supporting information; scheme or table, p. 9098 - 9101 (2012/07/14)
We report here an operationally simple, palladium-catalyzed cyclization reaction of N-aryl imines, affording indoles via the oxidative linkage of two C-H bonds under mild conditions using molecular oxygen as the sole oxidant. The process allows quick and atom-economical assembly of indole rings from inexpensive and readily available anilines and ketones and tolerates a broad range of functional groups.
Zinc-zinc bonded decamethyldizincocene Zn2(η5- C5Me5)2 as catalyst for the inter- and intramolecular hydroamination reaction
Luehl, Anja,Pada Nayek, Hari,Blechert, Siegfried,Roesky, Peter W.
scheme or table, p. 8280 - 8282 (2011/09/14)
The Zn-Zn bonded compound [(η5-Cp*)2Zn 2] was investigated as catalyst for the inter- and intramolecular hydroamination reaction. High reaction rates under mild conditions were observed. This is the first application of a
Highly enantioselective synthesis of chiral secondary amines by gold(I)/ chiral bronsted acid catalyzed tandem intermodular hydroamination and transfer hydrogenation reactions
Liu, Xin-Yuan,Che, Chi-Ming
scheme or table, p. 4204 - 4207 (2009/12/31)
A method for the synthesis of enantiomerically enriched secondary amines with excellent ee values through the tandem intermolecular hydroamination/ transfer hydrogenation of alkynes using a "gold(I) complex-chiral Bronsted acid" protocol is developed. The
