1268830-97-2

Basic information

• Product Name: 3-(((4-ethylphenyl)(methyl)amino)methyl)indolizine-1-carbonitrile
• Synonyms: 3-(((4-ethylphenyl)(methyl)amino)methyl)indolizine-1-carbonitrile
• CAS NO: 1268830-97-2
• Molecular Weight: 289.38
• Mol File: 1268830-97-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(((4-ethylphenyl)(methyl)amino)methyl)indolizine-1-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(((4-ethylphenyl)(methyl)amino)methyl)indolizine-1-carbonitrile(1268830-97-2)
• EPA Substance Registry System: 3-(((4-ethylphenyl)(methyl)amino)methyl)indolizine-1-carbonitrile(1268830-97-2)

Safety Data

• Hazardous Substances Data: 1268830-97-2(Hazardous Substances Data)

Upstream product

• 4150-37-2 N,N-dimethyl-4-ethylaniline 
• 3352-05-4 indolizine-1-carbonitrile 
• 589-16-2 4-aminoethylbenzene 

Relevant articles and documents

Copper-catalyzed oxidative cross-coupling of N,N-Dimethylanilines with heteroarenes under molecular oxygen

Nitrogen-containing heterocyclic compounds are important motifs of pharmaceuticals and functional materials, and there has been a growing interest in new synthetic methods for their preparation. In this paper, we report a direct cross-coupling reaction of heteroarenes with N,N-dimethylanilines in the presence of copper catalyst. Oxygen and/or air are successfully used as the oxidant, which is of great importance to the industrialized economies. The reaction is compatible with a wide range of heterocycles, including indolizines, imidazoles, indoles, and aniline, to enable the formation of various alkylated heteroarenes under very mild reaction conditions.