1269071-49-9Relevant academic research and scientific papers
SUBSTITUTES SULFONYL AZACYCLES AS MODULATORS OF HEDGEHOG (HH) SIGNALLING PATHWAY
-
Page/Page column 104, (2019/03/17)
There are described compounds of formula (I) in which X, R1, R2 and n are each as herein defined; and their use as a medicament in the treatment of conditions involving abnormal activation and/or malfunction of the hedgehog pathway,
A general and mild two-step procedure for the synthesis of aryl and heteroaryl sulfonamides from the corresponding iodides
Ho, Danny K.H.,Chan, Lily,Hooper, Alice,Brennan, Paul E.
scheme or table, p. 820 - 823 (2011/03/18)
A mild two-step preparation of aryl and heteroaryl sulfonyl chlorides and sulfonamides from their corresponding iodides is developed. Acid labile functionalities are shown to be stable under both the copper-catalysed coupling and the subsequent oxidative chlorination.
