126923-92-0Relevant academic research and scientific papers
Highly Stereoselective Synthesis of Both Enantiomers of 2-Methyl-3-Hydroxythioesters by Asymmetric Aldol Reactions Using Similar Types of Chiral Sources Derived from L-Proline
Kobayashi, Shu,Horibe, Mineko
, p. 1029 - 1030 (2007/10/03)
Both enantiomers of 2-methyl-3-hydroxythioesters have been synthesized in chiral tin(II) Lewis acid-mediated aldol reactions of silyl enolate 3 with aldehydes, by simply choosing similar types of chiral sources, 4 and 5, derived from L-proline.
Molecular recognition by artificial chiral catalysts utilizing a metal chelate. A remarkable difference in reactivity between geometrical isomers of silyl enolates in asymmetric aldol reactions using chiral Tin(II) catalysts
Kobayashi,Horibe,Hachiya
, p. 3173 - 3176 (2007/10/02)
A remarkable difference in reactivity between (E)- and (Z)-enolates in the asymmetric aldol reactions of silyl enolates with adehydes using chiral tin(II) Lewis acids was found. This difference can be interpreted to mean that the chiral catalyst coordinat
Catalytic asymmetric aldol-type reaction using a chiral tin(II) Lewis acid
Kobayashi,Uchiro,Shiina,Mukaiyama
, p. 1761 - 1772 (2007/10/02)
Highly diastereo- and enantioselective aldol-type reactions of a silyl enol ether with aldehydes including aromatic, aliphatic, and α,β-unsaturated ones are performed in propionitrile (solvent) by the use of a catalytic amount of chiral tin(II) Lewis acid
Asymmetric Aldol Reaction between Achiral Silyl Enol Ethers and Achiral Aldehydes by Use of a Chiral Promoter System
Kobayashi, Shu,Uchiro, Hiromi,Fujishita, Yuko,Shiina, Isamu,Mukaiyama, Teruaki
, p. 4247 - 4252 (2007/10/02)
In the presence of a chiral promoter consisting of tin(II) triflate, a chiral diamine, and tributyltin fluoride, the silyl enol ether of S-ethyl ethanethioate or S-tert-butyl ethanethioate reacts with aldehydes to afford the corresponding aldol-type adduc
An Efficient Chiral Promoter in the Aldol-type Reaction. Chiral Diamine Coordinated Tin(II) Triflate-Dibutyltindiacetate Complex
Mukaiyama, Teruaki,Uchiro, Hiromi,Kobayashi, Shu
, p. 1757 - 1760 (2007/10/02)
An efficient chiral promoter, chiral diamine coordinated tin(II) triflate-dibutyltindiacetate complex, promotes the asymmetric aldol type reaction between both achiral silyl enol ethers derived from thioesters and a wide variety of aldehydes in high yield
Perfect Stereochemical Control in the Synthesis of syn-α-Methyl-β-hydroxy Thioesters by Asymmetric Aldol Reaction of Silyl Enol Ethers with Aldehydes
Mukaiyama, Teruaki,Uchiro, Hiromi,Kobayashi, Shu
, p. 1001 - 1004 (2007/10/02)
Perfect stereochemical control in the synthesis of syn-α-methyl-β-hydroxy thioesters are achieved by the asymmetric aldol reaction between silyl enol ether of S-ethyl propanethioate and aldehydes by the use of a chiral promoter consisted of chiral diamine
