127801-80-3Relevant academic research and scientific papers
Catalytic asymmetric aldol-type reaction using a chiral tin(II) Lewis acid
Kobayashi,Uchiro,Shiina,Mukaiyama
, p. 1761 - 1772 (2007/10/02)
Highly diastereo- and enantioselective aldol-type reactions of a silyl enol ether with aldehydes including aromatic, aliphatic, and α,β-unsaturated ones are performed in propionitrile (solvent) by the use of a catalytic amount of chiral tin(II) Lewis acid
A New Efficient Chiral Catalyst System. Combined Use of Tin(II) Oxide, Trimethylsilyl Triflate and Chiral Diamine in the Asymmetric Aldol Reaction
Mukaiyama, Teruaki,Uchiro, Hiromi,Kobayashi, Shu
, p. 1147 - 1150 (2007/10/02)
The asymmetric aldol reaction between both achiral silyl enol ethers of thioesters and aldehydes is efficiently catalyzed by the use of a new catalyst system consisted of tin(II) oxide, trimethylsilyl triflate and a chiral diamine, to give the corresponding adducts in high yields with high diastereo- and enantioselectivities.
