1269428-59-2Relevant academic research and scientific papers
Synthesis of a family of cyclic peptide-based anion receptors
Butler, Stephen J.,Jolliffe, Katrina A.
experimental part, p. 3471 - 3483 (2011/06/25)
We report here the design and synthesis of a family of novel backbone modified cyclic peptides, bearing dipicolylamine side chains for metal complexation and subsequent anion binding studies. Two approaches to the cyclic peptides were investigated. Initia
Synthesis of backbone modified cyclic peptides bearing dipicolylamino sidearms
Butler, Stephen J.,Jolliffe, Katrina A.,Lee, Wee Yu Gladys,McDonough, Matthew J.,Reynolds, Aaron J.
, p. 1019 - 1029 (2011/03/19)
Three analogues of the Lissoclinum class of cyclic peptides, bearing dipicolylamino functionalised side chains, have been synthesised using a stepwise approach followed by macrocyclisation. Attempts to incorporate dipicolylamino functionalised side chains prior to peptide synthesis resulted in epimerisation, but this was overcome by functionalising the ornithine side chains with dipicolylamino groups after the macrocyclisation reaction.
