1269499-79-7

Basic information

• Product Name: C₂₂H₂₇N₃O₇S
• CAS NO: 1269499-79-7
• Molecular Weight: 477.538
• Mol File: 1269499-79-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₇N₃O₇S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₇N₃O₇S(1269499-79-7)
• EPA Substance Registry System: C₂₂H₂₇N₃O₇S(1269499-79-7)

Safety Data

• Hazardous Substances Data: 1269499-79-7(Hazardous Substances Data)

Upstream product

• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 
• 1269499-78-6 C₁₄H₁₈N₂O₆S 
• 2735-04-8 2,4-Dimethoxyaniline 
• 1269499-77-5 C₁₅H₂₀N₂O₆S 
• 342779-23-1 C₁₂H₁₆N₂O₄S 
• 34376-54-0 [1,4]diazepan-5-one 

Relevant articles and documents

Solution-phase parallel synthesis and SAR of homopiperazinyl analogs as positive allosteric modulators of mGlu4

Using a functional high-throughput screening (HTS) and subsequent solution-phase parallel synthesis approach, we have discovered a novel series of positive allosteric modulators formGlu4, a G-protein coupled receptor. This series is comprised of a homopiperazine central core. The solution-phase parallel synthesis and SAR of analogs derived from this series will be presented. This series of positive allosteric modulators of mGlu4 provide critical research tools to further probe the mGlu4-mediated effects in Parkinson's disease.