1269646-82-3Relevant academic research and scientific papers
SUBSTANCE FOR INHIBITION OF GLYCINE TRANSPORTER
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, (2020/04/21)
PROBLEM TO BE SOLVED: To provide a new compound or its pharmaceutically acceptable salt useful for preventing or treating diseases such as integrated dystonia, Alzheimer disease, cognitive dysfunction, dementia, anxiety disorder(such as global anxiety disorder, panic disorder, obsessive compulsive disorder, social anxiety disorder, post traumatic stress disorder, particular phobia, acute stress disorder), depression, drug dependence, convulsion, trembling, ache, Parkinson disease, attention-deficit/hyperactivity disorder, bipolar disorder, eating disorder or sleep disorder, based on inhibitory effect on glycine uptake. SOLUTION: There are provided a compound represented by the formula [I] or its pharmaceutically acceptable salt. COPYRIGHT: (C)2015,JPOandINPIT
GLYCINE TRANSPORTER-INHIBITING SUBSTANCES
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, (2014/01/08)
The present invention relates to novel compounds of formula [I] or pharmaceutically acceptable salts thereof: The compounds of the present invention are useful in the prevention or treatment of diseases such as schizophrenia, Alzheimer's disease, cognitive impairment, dementia, anxiety disorders (e.g., generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, post-traumatic stress disorder, specific phobias, acute stress disorder), depression, drug dependence, spasm, tremor, pain, Parkinson's disease, attention deficit hyperactivity disorder, bipolar disorder, eating disorder, or sleep disorders, which is based on the glycine uptake-inhibiting action.
SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS
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, (2011/04/14)
Compounds of Formula I: and salts thereof in which R1, R2, R2a, R3, n, X and ring B have the meanings given in the specification, are inhibitors of mTOR and are useful in the treatment of diseases which are sensitive to inhibition of mTOR, such as cancers.
