1269771-43-8

Basic information

• Product Name: 5-chloro-N-[2-(methylamino)phenyl]-2-(methylthio)pyrimidine-4-carboxamide
• Synonyms: 5-chloro-N-[2-(methylamino)phenyl]-2-(methylthio)pyrimidine-4-carboxamide
• CAS NO: 1269771-43-8
• Molecular Weight: 308.791
• Mol File: 1269771-43-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-chloro-N-[2-(methylamino)phenyl]-2-(methylthio)pyrimidine-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-N-[2-(methylamino)phenyl]-2-(methylthio)pyrimidine-4-carboxamide(1269771-43-8)
• EPA Substance Registry System: 5-chloro-N-[2-(methylamino)phenyl]-2-(methylthio)pyrimidine-4-carboxamide(1269771-43-8)

Safety Data

• Hazardous Substances Data: 1269771-43-8(Hazardous Substances Data)

Upstream product

• 61727-33-1 5-chloro-2-(methylthio)pyrimidine-4-carboxylic acid 
• 4760-34-3 N-methyl-1,2-phenylenediamine 

Relevant articles and documents

BENZIMIDAZOLE DERIVATIVES

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1A, R1B, R1C, R2, R3, R4, R5, RA, RB, RC and X are as defined herein. These novel benzimidazole derivatives are useful in therapy, in particular for treating diseases or conditions mediated by SMO, including the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.