61727-33-1 Usage
Uses
5-Chloro-2-(methylthio)-4-pyrimidinecarboxylic acid is a synthetic intermediate in the preparation of GSK3β inhibitors and non-nucleoside reverse transcriptase inhibitors for treating HIV infection.
Check Digit Verification of cas no
The CAS Registry Mumber 61727-33-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,7,2 and 7 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 61727-33:
(7*6)+(6*1)+(5*7)+(4*2)+(3*7)+(2*3)+(1*3)=121
121 % 10 = 1
So 61727-33-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H5ClN2O2S/c1-12-6-8-2-3(7)4(9-6)5(10)11/h2H,1H3,(H,10,11)
61727-33-1Relevant articles and documents
General and facial synthesis of 2-amino-5-halogenpyrimidine-4-carboxylic acids and their derivatives
Blyumin, Evgeniy V.,Neunhoeffer, Hans,Volovenko, Yulian V.
, p. 2231 - 2241 (2008/02/07)
A facile synthetic approach to 2-amino-5-halogen-pyrimidine-4-carboxylic acids from 5-halogen-2-methylsulfonylpyrimidine-4-carboxylic acid by nucleophilic displacement of the methylsulfonyl group with primary and secondary aliphatic amines has been develo
On the synthesis of 4- and 5-pyrimidinyl-diphenyl-(1-imidazolyl)methanes and their antifungal activity
Budesinsky,Vavrina,Langsadl,Holubek
, p. 539 - 547 (2007/10/02)
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