1269818-12-3

Basic information

• Product Name: 2-tert-butyl 1-ethyl 3-(5-fluoro-2-methoxyphenyl)-4,5,6,7-tetrahydro-2H-isoindole-1,2-dicarboxylate
• Synonyms: 2-tert-butyl 1-ethyl 3-(5-fluoro-2-methoxyphenyl)-4,5,6,7-tetrahydro-2H-isoindole-1,2-dicarboxylate
• CAS NO: 1269818-12-3
• Molecular Weight: 417.477
• Mol File: 1269818-12-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-tert-butyl 1-ethyl 3-(5-fluoro-2-methoxyphenyl)-4,5,6,7-tetrahydro-2H-isoindole-1,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tert-butyl 1-ethyl 3-(5-fluoro-2-methoxyphenyl)-4,5,6,7-tetrahydro-2H-isoindole-1,2-dicarboxylate(1269818-12-3)
• EPA Substance Registry System: 2-tert-butyl 1-ethyl 3-(5-fluoro-2-methoxyphenyl)-4,5,6,7-tetrahydro-2H-isoindole-1,2-dicarboxylate(1269818-12-3)

Safety Data

• Hazardous Substances Data: 1269818-12-3(Hazardous Substances Data)

Upstream product

• 1269818-09-8 2-tert-butyl 1-ethyl 3-bromo-4,5,6,7-tetrahydro-2H-isoindole-1,2-dicarboxylate 
• 179897-94-0 (5-fluoro-2-methoxyphenyl)boronic acid 
• 2999-46-4 Ethyl isocyanoacetate 
• 2562-37-0 1-nitrocyclohexene 
• 65880-17-3 ethyl 4,5,6,7-tetrahydro-2H-isoindole-1-carboxylate 

Downstream Products

• 1269818-16-7 1-(5-fluoro-2-methoxyphenyl)-4,5,6,7-tetrahydro-2H-isoindole 
• 1269818-19-0 3,3'-(phenylmethylene)bis(1-(5-fluoro-2-methoxyphenyl)-4,5,6,7-tetrahydro-2H-isoindole) 
• 1269818-23-6 BCC₆H₅(C₈H₈NC₆H₃FO)2 

Relevant articles and documents

Manganese(III) complexes of bis(hydroxyphenyl)dipyrromethenes are potent orally active peroxynitrite scavengers

We report a new series of biscyclohexano-fused Mn(III) complexes of bis(hydroxyphenyl)dipyrromethenes, 4a-c, as potent and orally active peroxynitrite scavengers. Complexes 4a-c are shown to reduce peroxynitrite through a two-electron mechanism, thereby forming the corresponding Mn(V)O species, which were characterized by UV, NMR, and LC-MS methods. Mn(III) complex 4b and its strained BODIPY analogue 9b were analyzed by X-ray crystallography. Finally, complex 4a is shown to be an orally active and potent analgesic in a model carrageenan-induced hyperalgesia known to be driven by the overproduction of peroxynitrite.