126985-27-1

Upstream product

• 72740-50-2 4-amino-6-phenyl-5-cyano-2-cyclohexanespiro-1,3-dithia-4-cyclohexene 
• 17282-41-6 N-acetonylpyridinium bromide 
• 94639-04-0 6-Amino-2,2-dimethyl-4-phenyl-4H-[1,3]dithiine-5-carbonitrile 
• 102434-73-1 2,6-diamino-4-phenyl-3,5-dicyano-4H-thiopyran 

Downstream Products

• 78564-23-5 6-methyl-4-phenyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile 

Relevant academic research and scientific papers

CYCLIZATION OF NITRILES. XLIX. DEGENERATED STEREOSELECTIVE CROSS-RECYCLIZATION OF ENAMINONITRILES OF THE 1,3-DITHIACYCLOHEXENE AND 4H-THIOPYRAN SERIES WITH PYRIDINIUM YLIDES INTO SUBSTITUTED 3-(PYRIDINIO)-5-CYANO-3,4-TRANS-1,2,3,4-TETRAHYDRO-6-PYRIDINE-THIOLATES

The reactions of enaminonitriles of 1,3-dithiacyclohexenes and 4H-thiopyrans with pyridinium ylides proceed highly regio- and stereoselectively according to the cross-recyclization mode with the formation of substituted 3-(1-pyridino)-5-cyano-3,4-trans-1,2,3,4-tetrahydro-6-pyridinethiolates.These reactions have a common intermediate, arylmethylenecyanothioacetamide, which was used in the synthesis of substituted 6-pyridinethiolates.Because of the common nature of the structure of the initial enaminonitriles of 1,3-dithiacyclohexenes and 4H-thiopyrans, the intermediate compounds and the reaction end products, the above recyclization reactions were designated as degenerated reactions.