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126988-82-7

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126988-82-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 126988-82-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,9,8 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 126988-82:
(8*1)+(7*2)+(6*6)+(5*9)+(4*8)+(3*8)+(2*8)+(1*2)=177
177 % 10 = 7
So 126988-82-7 is a valid CAS Registry Number.

126988-82-7Relevant articles and documents

Design, Synthesis, and 5-Lipoxygenase-Inhibiting Properties of 1-Thio-Substiuted Butadienes

Hanko, Rudolf,Hammond, Michael D.,Fruchtmann, Romanis,Pfitzner, Joerg,Place, Graham A.

, p. 1163 - 1170 (2007/10/02)

The synthesis of novel 1-thio-substituted butadienes, designed as mechanism-based 5-lipoxygenase inhibitors, is described.The structure of these compounds closely resembles a proposed high-energy intermediate during the lipoxygenation of arachidonic acid.They demonstrate 5-lipoxygenase inhibition in vitro and in vivo.The most potent compound is 15a with an IC50 of μM in vitro.LTC4 release was inhibited by 80percent after intraperitoneal administration of 15c at a dose of 2 mg/kg.

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