1269992-35-9Relevant academic research and scientific papers
Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies
Sudhapriya,Perumal,Balachandran,Ignacimuthu,Sangeetha,Doble, Mukesh
, p. 190 - 207 (2014)
A series of 25 new spirocarbocycles were synthesized by a three component reaction that involves few cyclic nucleophiles, vinyl malononitriles and aldehydes with variable substitution patterns. All the synthesized compounds were evaluated for their antimi
Uses of cyclohexan-1,3-dione for the synthesis of thiazole, pyrazole, thiophene, isoxazole and pyran derivatives with antitumor activities
Abdo, Nadia Youssef Megally,Al-Darkazali, Waleed Nabeel,Mohareb, Rafat Milad
, p. 595 - 607 (2020/04/17)
Background: A wide range of thiazole, pyrazole and pyran derivatives gained special attention due to pharmacological activities especially therapeutic activities. Many pharmacological drugs containing the thiazole and pyrazole nuclei are known in the mark
Facile one-pot synthesis of chromeno[4,3-b] quinoline derivatives catalyzed by Cu(II)-Schiff base/SBA-15
Motamedi, Radineh,Bardajee, Ghasem Rezanejade,Shakeri, Somaye
, p. 181 - 184 (2014/07/07)
A novel, one-pot, simple, environmentally benign and efficient protocol has been employed for the synthesis of chromeno[4,3-b]quinoline derivatives in the presence of catalytic amounts of Cu(II)-Schiff base/SBA-15 under solvent-free conditions in excellen
Design, synthesis and evaluation of cytotoxicity of novel chromeno[4,3-b]quinoline derivatives
Miri, Ramin,Motamedi, Radineh,Rezaei, Mohammad Reza,Firuzi, Omidreza,Javidnia, Azita,Shafiee, Abbas
experimental part, p. 111 - 118 (2011/09/19)
In the present work 15 new 1,4-dihydropyridines (DHPs) bearing a coumarin ring were synthesized and assessed on 4 different human cancer cell lines (HeLa, K562, LS180, and MCF-7). Although, all the derivatives were inactive on LS180 cell line, the results
