127039-17-2Relevant academic research and scientific papers
Mannich Reaction with 1,3-Indandione Phenylhydrazones
Afsah, E. M.,Hammouda, M.,Zoorob, H.,Khalifa, M. M.,Zimaity, M. T.
, p. 80 - 82 (2007/10/02)
Mannich reaction of 1,3-indandione-1-phenylhydrazone (1) or 1,3-diphenylhydrazone (5) with morpholine or piperazine gave the Mannich base-phenylhydrazone 2 and 3 or the diphenylhydrazone 6 and 7, respectively.Whereas, such reaction with 1 or 5 using primary amines afforded the indeno-1,2,4-triazepin-6(2H)-one (4) or its 6-phenylhydrazone (8), respectively.Treatment of 5 with ammonium acetate and formalin afforded 9.The indeno-1,2,4,5-tetrazepin-10(2H)-one (11) was obtained from the 1,2-diphenylhydrazone 10 and formaldehyde.
