127040-68-0

Upstream product

• 7341-63-1 1-allyl-3-phenyl-thiourea 

Downstream Products

• 138841-35-7 2-(Acetyl-phenyl-amino)-7-ethoxycarbonylmethyl-6-oxa-1-thia-3-aza-spiro[4.4]nona-2,7-diene-8-carboxylic acid ethyl ester 
• 138841-33-5 C₂₀H₂₂N₂O₃S 
• 138841-32-4 2-(Acetyl-phenyl-amino)-7-methyl-6-oxa-1-thia-3-aza-spiro[4.4]nona-2,7-diene-8-carboxylic acid ethyl ester 
• 138841-34-6 N-(8-Acetyl-7-methyl-6-oxa-1-thia-3-aza-spiro[4.4]nona-2,7-dien-2-yl)-N-phenyl-acetamide 
• 127040-78-2 (2-Phenylamino-4,5-dihydro-thiazol-5-yl)-methanol 
• 127040-84-0 N-(5-Methylene-4,5-dihydro-thiazol-2-yl)-N-phenyl-acetamide 
• 52829-88-6 5-methylene-N-phenyl-4,5-dihydrothiazol-2-amine 
• 127040-80-6 Phenyl-(5-phenylsulfanylmethyl-4,5-dihydro-thiazol-2-yl)-amine 

Relevant academic research and scientific papers

A general route to spirocycles by radical additions to exocyclic unsaturated sulphides and related compounds

Manganic acetate promoted additions of β-dicarbonyl compounds to unsaturated sulphides and enamine derivatives, which are readily available via iodocyclisation of unsaturated substrates, and subsequent elimination, afford spirocyclic systems.

SYNTHESIS AND ELABORATION OF HETEROCYCLES VIA IODOCYCLISATION OF UNSATURATED THIOUREAS

Iodocyclisation of N-allyl or S-allyl thioureas leads efficiently to dihydrothiazoles, and dihydroimidazoles and homologous thioureas afford dihydrothiazines.The products are readily elaborated to give unusual heterocyclic systems.