52829-88-6Relevant academic research and scientific papers
Ag(i)-Catalyzed rapid access to 2-amino-4-methylenethiazolines with potential applications in bioconjugation chemistry
Xiang, Lingling,Wu, Haiting,Liang, Yunshi,Deng, Huiying,He, Yiting,Xu, Qin,Zhang, Jing
, p. 4060 - 4066 (2021)
An Ag(i)-catalyzed tandem addition-cyclization of isothiocyanate and propargylamine was successfully applied to the synthesis of 2-amino-4-methylenethiazolines. This route features an unprecedented fast reaction rate with full conversion reached within 10
Microwave-Assisted Domino Reactions of Propargylamines with Isothiocyanates: Selective Synthesis of 2-Aminothiazoles and 2-Amino-4-methylenethiazolines
Scalacci, Nicoló,Pelloja, Chiara,Radi, Marco,Castagnolo, Daniele
supporting information, p. 1883 - 1887 (2016/07/16)
A simple and versatile microwave-assisted protocol for the synthesis of 2-aminothiazoles has been developed. The domino reaction of propargylamines and isothiocyanates in the presence of catalytic PTSA leads to the selective synthesis of 2-aminothiazoles
SYNTHESIS AND ELABORATION OF HETEROCYCLES VIA IODOCYCLISATION OF UNSATURATED THIOUREAS
Creeke, Paul I.,Mellor, John M.
, p. 4435 - 4438 (2007/10/02)
Iodocyclisation of N-allyl or S-allyl thioureas leads efficiently to dihydrothiazoles, and dihydroimidazoles and homologous thioureas afford dihydrothiazines.The products are readily elaborated to give unusual heterocyclic systems.
