127055-22-5Relevant academic research and scientific papers
Preparation of 3-Alkyl β-Lactams via the Ketene-Imine Cycloaddition Reaction Using α-(Phenylthio)alkanoyl Halides as Starting Materials:Application to the Synthesis of (+/-)-Carbapenem Building Blocks and Related Compounds
Palomo, Claudio,Cossio, Fernando P.,Odiozola, Jose M.,Oiarbide, Mikel,Ontoria, Jesus M.
, p. 4418 - 4428 (2007/10/02)
Preparation of appropriately substituted 3-alkyl β-lactams via the ketene (or equivalent)-imine cycloaddition reaction is described.The dehydrochlorination reaction of α-(phenylthio)alkanoyl chlorides with triethylamine in the presence of imines derived f
Alkyl(phenylthio)ketenes as Synthetic Equivalents of Monoalylketenes: A Concise General Route To 3-Alkyl β-Lactams as Carbapenem Building-Blocks
Palomo, Claudio,Cossio, Fernando P.,Odriozola, Jose M.,Oiarbide, Mikel,Ontoria, Jesus M.
, p. 4577 - 4580 (2007/10/02)
The dehydrochlorination of α-phenylthioalkanoyl chlorides with triethylamine in presence of imines produced a high yield formation of α-phenylthio β-lactams which upon desulfuration furnished a wide variety of 3-alkyl β-lactams in a high stereoselective f
