124156-20-3

Upstream product

• 922-68-9 Methyl glyoxylate 
• 104-94-9 4-methoxy-aniline 
• 6290-49-9 methyl methoxyacetate 
• 109745-70-2 methyl glyoxylate methyl hemi-acetal 
• 147749-35-7 2-(4-methoxyphenylamino)acetic acid methyl ester 
• 50845-77-7 N-(4-methoxy)phenylglycine ethyl ester 

Downstream Products

• 124175-15-1 cis-1-p-anisyl-3-(1'-methylvinyl)-4-carbomethoxy-2-azetidinone 
• 124156-22-5 cis-1-(4-Methoxyphenyl)-3-vinyl-4-(methoxycarbonyl)-2-azetidinone 
• 128571-96-0 (1'S^*,3R^*,4S^*)-3-<1-(dimethylphenylsilyl)ethyl>-4-methoxycarbonyl-1-(4-methoxyphenyl)azetidin-2-one 
• 131533-38-5 (2R,3S)-3-[1-(Dimethyl-phenyl-silanyl)-1-methyl-ethyl]-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid methyl ester 
• 80542-45-6 cis-3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-4-(methoxycarbonyl)-1-(4-methoxyphenyl)-2-oxazetidine 
• 135616-64-7 (2S,3S)-1-(4-Methoxy-phenyl)-3-methyl-4-oxo-3-phenylsulfanyl-azetidine-2-carboxylic acid methyl ester 
• 135616-64-7 (2R,3S)-1-(4-Methoxy-phenyl)-3-methyl-4-oxo-3-phenylsulfanyl-azetidine-2-carboxylic acid methyl ester 
• 131533-37-4 (2R,3S)-3-[(S)-(Dimethyl-phenyl-silanyl)-p-tolyl-methyl]-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid methyl ester 
• 138331-59-6 (2S,3S)-3-[(S)-(Dimethyl-phenyl-silanyl)-p-tolyl-methyl]-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid methyl ester 
• 131533-36-3 (2R,3S)-3-[(S)-(Dimethyl-phenyl-silanyl)-phenyl-methyl]-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid methyl ester 
• 131614-09-0 (2S,3S)-3-[(S)-(Dimethyl-phenyl-silanyl)-phenyl-methyl]-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid methyl ester 
• 124156-23-6 3-ethyl-4-methoxycarbonyl-1-(4-methoxyphenyl)azetidin-2-one 
• 124156-26-9 cis-3-Isopropyl-4-(methoxycarbonyl)-1-(4-methoxyphenyl)azetidin-2-one 
• 128474-79-3 trans-3-Isopropyl-4-(methoxycarbonyl)-1-(4-methoxyphenyl)azetidin-2-one 

Relevant academic research and scientific papers

Combining visible light catalysis and transition metal catalysis for the alkylation of secondary amines

By combining the visible-light catalyst, Ru (bpy) 3Cl 2, and transition metal salts, Cu (OTf)2, we are able to functionalize secondary amines to form Csp3-Csp3 bonds with b-keto esters efficiently by

Metal-free photocatalyzed aerobic oxidative Csp3-H functionalization of glycine derivatives: One-step generation of quinoline-fused lactones

A metal-free aerobic oxidative dehydrogenative coupling/annulation tandem reaction of glycine derivatives to 2,3-dihydrofuran is disclosed. This process involves the synergistic performance of organic-dye-mediated photoredox catalysis and acid catalysis.

Regioselective synthesis of pyrroloquinolines - Approaches to Martinelline

Indium trichloride catalysed Diels-Alder reaction of imines derived from anilines with cyclic enamides regioselectively gave the biologically important pyrroloquinoline nucleus, with a cis ring junction, in moderate yield. Although the exo:endo selectivity was in most cases poor, these isomers are readily separated by flash chromatography. The functionality tolerated at both C2 and C7 should allow further elaboration to Martinelline.

Tin powder-promoted oxidation/allylation of glycine esters: Synthesis of γ,δ-unsaturated α-amino acid esters

An efficient tin powder-promoted oxidation/allylation reaction of glycine esters with allyl bromides is developed, which affords γ,δ-unsaturated α-amino acid esters under mild conditions without any other transition metal catalysts. This method avoids the use of unstable imine as starting material, and provides an efficient method for synthesis of γ,δ-unsaturated α-amino acid esters and α-methylene-γ-lactam derivatives. Additional supporting information may be found in the online version of this article at the publisher's web site.

Enantioselective intermolecular carbon-carbon bond formation of glyoxylate imines with allylstannanes catalyzed by tropos BIPHEP-gold(I) complexes with Au-Au interactions

Interactions act: The enantioselective allylation reaction of glyoxylate imines catalyzed by tropos DM-BIPHEP-gold(I) complexes with an Au-Au interaction was developed to give a higher enantioselectivity than the atropos DM-BINAP-gold complexes without an

3-(Heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents

The present invention relates to novel Syn isomers of racemates and optical isomers of 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids of formula (I) and its use in treating the infections caused by gram-negative pathogenic bacteria.

Stereoselective synthesis of racemic α-amino-acid derivatives with a β-lactam skeleton: Application of the Staudinger reaction to chiral imines of methyl glyoxylate

Selected imines of methyl glyoxylate act as good partners in the Staudinger cycloaddition reaction with a series of substituted ketenes. The cis stereoselectivity is almost complete with electron-donor substituted ketenes, but the asymmetric induction is low when imines derived from chiral l-aryl-ethylamines are used.

β-Lactams via α,β-Unsaturated Acid Chlorides: Intermediates for Carbapenem Antibiotics

Stereocontrolled synthesis of α-vinyl β-lactams and their transformation to convenient intermediates for PS-5, PS-6, asparenomycin, and thienamycin are described.

2-OXO-1-AZETIDINESULFONIC ACID SALTS

Antibacterial activity is exhibited by beta-lactams having a sulfonic acid salt substituent in the 1-position and an amino or acylamino substituent in the 3-position.