12706-94-4

Basic information

• Product Name: hikizimycin
• Synonyms: hikizimycin;4-Amino-1-[4-amino-6-O-(3-amino-3-deoxy-β-D-glucopyranosyl)-4-deoxy-D-glycero-D-galacto-β-D-gluco-undecopyranosyl]-2(1H)-pyrimidinone;1402-84-2 (Deleted);1-N-(2-o-(3-Amino-3-deoxy-.beta.-D-glucopyranosyl)-4-amino-4-deoxy-D-glycero-D-gal acto-D-gluco-.beta.-D-undecapyranosyl)cytosine;2(1H)-Pyrimidinone, 4-amino-1-[4-amino-6-o-(3-amino-3-deoxy-.beta.-D-glucopyranosyl)-4-deoxy-D-glycero-D-galacto-.beta.-D-gluco-undecopyranosyl]-;Aids029905;Aids-029905;Nsc337588
• CAS NO: 12706-94-4
• Molecular Formula: C21H37N5O14
• Molecular Weight: 583.544
• Mol File: 12706-94-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 641.06°C (rough estimate)
• Flash Point: 576.8°C
• Appearance: /
• Density: 1.4619 (rough estimate)
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.7850 (estimate)
• CAS DataBase Reference: hikizimycin(CAS DataBase Reference)
• NIST Chemistry Reference: hikizimycin(12706-94-4)
• EPA Substance Registry System: hikizimycin(12706-94-4)

Safety Data

• Hazardous Substances Data: 12706-94-4(Hazardous Substances Data)

Usage

Definition

ChEBI: A nucleoside antibiotic with anthelminthic properties that is isolated from Streptomyces longissimus.

Safety Profile

Poison by ingestion andintravenous routes. When heated to decomposition itemits toxic fumes of NOx.

InChI:InChI=1/C21H37N5O14/c22-7-1-2-26(21(37)25-7)19-16(36)12(32)9(24)17(39-19)18(15(35)14(34)10(30)5(29)3-27)40-20-13(33)8(23)11(31)6(4-28)38-20/h1-2,5-6,8-20,27-36H,3-4,23-24H2,(H2,22,25,37)/t5-,6+,8-,9-,10-,11+,12-,13+,14-,15-,16+,17-,18?,19+,20-/m0/s1

Upstream product

• 139631-37-1 3-azido-1,3-dideoxy-1-(phenylsulfenyl)-2,4,6-tri-O-acetyl-β-D-gluco-pyranose 
• 139631-53-1 3-azido-1,3-dideoxy-1-(phenylsulfenyl)-2,4,6-tri-O-(2,2-dimethylpropanoyl)-β-D-glucopyranose 
• 205676-46-6 phenyl 3-azido-3-deoxy-1-thio-β-D-glucopyranoside 
• 185114-94-7 1,2,4,6-Tetra-O-acetyl-3-azido-3-deoxy-α/β-gluco-hexopyranose 
• 130861-02-8 3-azido-1,3-dideoxy-1-(phenylsulfinyl)-2,4,6-tri-O-(2,2-dimethylpropanoyl)-β-D-glucopyranose 

Related news

The structure of hikizimycin (cas 12706-94-4) : Part I. Identification of 3-amino-3-deoxy-D-glucose and cytosine as structural components☆08/25/2019

The molecular formula for hikizimycin, a new antibiotic isolated from Streptomyces A-5, is now established as C21H37N5O14. Evidence in support of the occurrence of 3-amino-3-deoxy-D-glucose and cytosine residues in the antibiotic molecules is presented. Methanolysis of N,N′-diacetylhikizimycin ...detailed

13C NMR investigations of the nucleoside antibiotic hikizimycin (cas 12706-94-4) and its constituents08/23/2019

Confirmation of the structure of the nucleoside antibiotic hikizimycin was obtained by comparing the 13C NMR chemical shift data of selected model compounds with hikizimycin and its constituents.detailed

Relevant articles and documents

Convergent Total Synthesis of Hikizimycin Enabled by Intermolecular Radical Addition to Aldehyde

Hikizimycin (1), which exhibits powerful anthelmintic activity, has the most densely functionalized structure among nucleoside antibiotics. A central 4-amino-4-deoxyundecose of 1 possesses 10 contiguous stereocenters on a C1-C11 linear chain and is decora

Total synthesis of the anthelmintic agent hikizimycin

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