127064-91-9Relevant academic research and scientific papers
Ozonide compounds with inhibitory activity for urokinase production and angiogenesis
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, (2008/06/13)
The invention provides a urokinase production inhibitor or angiogenesis inhibitor comprising as an active component an ozonide derivative represented by the formula (1), and method of prevention or therapy using the inhibitor wherein A is an oxygen atom o
Cycloaddition between Carbonyl Oxides and Dicarbonyl Compounds: Isolation and Characterization of Novel Polycyclic 1,2,4,6-Tetroxepane Derivatives
McCullough, Kevin J.,Sugimoto, Toshiya,Tanaka, Shogo,Kusabayashi, Shigekazu,Nojima, Masatomo
, p. 643 - 652 (2007/10/02)
Formaldehyde O-oxide reacts with dicarbonyl compounds to produce mono-ozonides formed by conventional cycloadditions to an aldehyde carbonyl group of the substrate, and/or polycyclic 1,2,4,6-tetroxepane derivatives arising from formal cycloadditions involving both carbonyl groups.Similar reactions between the more highly substituted carbonyl oxides, benzaldehyde and octanal O-oxides, and dicarbonyl compounds yielded the corresponding mono-ozonides as the sole isolable cycloaddition products.In certain favorable cases, mono-ozonides could undergo acid-catalysed intramolecular rearrangement to the corresponding 1,2,4,6-tetroxepanes.X-Ray crystallographic analyses of two 1,2,4,6-tetroxepanes, 6a and 13b, are recorded.
Ozonolysis of Acenaphthylene and 1-Substituted Acenaphthylenes
Sugimoto, Toshiya,Nojima, Masatomo,Kusabayashi, Shigekazu
, p. 3816 - 3820 (2007/10/02)
The ozonolysis of 1-methylacenaphthylene (1b) and acenaphthylene (1c) in carbon tetrachloride, acetonitrile, acetic acid, and trifluoroethanol revealed that the ozonide yield was much higher in reactions in protic solvents than in aprotic solvents.Such an
