127066-49-3Relevant academic research and scientific papers
Electrochemical oxidative decarboxylation and 1,2-aryl migration towards the synthesis of 1,2-diaryl ethers
Bu, Faxiang,Hu, Xia,Lei, Aiwen,Lu, Lijun,Wang, Shengchun,Zhang, Heng
, p. 10000 - 10004 (2020/10/06)
Carboxylic acid compounds are important chemicals and are widely present in various natural products. They are not only nucleophiles, but also radical precursors. Classic transition-metal-catalyzed and photochemical decarboxylation have shown their excellent site selectivity in radical chemistry. However, electrochemical decarboxylation with a long history hasn't got enough attention in recent years. In this work, the electrochemical oxidative decarboxylation and 1,2-aryl migration of 3,3-diarylpropionic acids have been introduced to construct C-O bonds with alcohols. Remarkably, this transformation can proceed smoothly without metal catalysts and external oxidants.
Transition-Metal-Free Catalytic Carboalkoxylation of Styrenes at Room Temperature
Govindarajan,Ahmed, Jasimuddin,Swain, Asim Kumar,Mandal, Swadhin K.
, p. 13490 - 13502 (2019/10/16)
Herein, we describe the first transition-metal-free catalytic carboalkoxylation of styrenes with aryl diazonium salts by Meerwein addition in the presence of a phenalenyl ligand at room temperature without requiring any light stimulation. This three-compo
Oxyarylation and aminoarylation of styrenes using photoredox catalysis
Fumagalli, Gabriele,Boyd, Scott,Greaney, Michael F.
supporting information, p. 4398 - 4401 (2013/09/24)
A three-component coupling of styrenes is reported, using photoredox catalysis to achieve simultaneous arylation and C-O or C-N bond formation across the styrene double bond.
Gold-catalysed oxyarylation of styrenes and mono- and gem-disubstituted olefins facilitated by an iodine(III) oxidant
Ball, Liam T.,Lloyd-Jones, Guy C.,Russell, Christopher A.
supporting information; experimental part, p. 2931 - 2937 (2012/04/23)
1-Hydroxy-1,2-benziodoxol-3(1H)-one (IBA) is an efficient terminal oxidant for gold-catalysed, three-component oxyarylation reactions. The use of this iodine(III) reagent expands the scope of oxyarylation to include styrenes and gem-disubstituted olefins, substrates that are incompatible with the previously reported Selectfluor-based methodology. Diverse arylsilane coupling partners can be employed, and in benzotrifluoride, homocoupling is substantially reduced. In addition, the IBA-derived co-products can be recovered and recycled. The I's have it: The unprecedented use of an iodine(III) reagent as the terminal oxidant for gold-catalysed oxyarylation allows the substrate scope to be significantly expanded; in addition to monosubstituted olefins, styrenes and gem-disubstituted olefins are well tolerated (see scheme). With benzotrifluoride as solvent, unproductive homodimerisation of the arylsilane coupling partner is effectively suppressed. Copyright
