127074-75-3

Upstream product

• 67-56-1 methanol 
• 127074-84-4 1-(2-Hydroxy-2-phenylethyl)-4-piperidinol 
• 127074-72-0 1-Phenyl-2-(1,2,3,6-tetrahydropyridin-1-yl)-ethanol 
• 532-27-4 1-chloroacetophenone 
• 86518-55-0 2-(4-Hydroxypiperidino)-1-phenyl-ethanon 
• 5382-16-1 4-HYDROXYPIPERIDINE 

Relevant academic research and scientific papers

Sodium mercury edetate dehydrogenation of N-aliphatic substituted 1,2,3,6-tetrahydropyridine derivatives

Hg(II)-edta dehydrogenation of N-aliphatic substituted Δ3-piperideine 1 leads to polymers. From 4 carrying a hydroxy neighbour group in the aliphatic side chain, it is possible to yield definite oxidation products - in dependence of nucleophiles present - mainly 4-substituted piperidone-2 derivatives 5 and 9-12. The oxidation of corresponding 4-hydroxy- (19) or 4-amino- (20, 21) piperidines gives the same spectrum of products. A mechanism for all the reactions is proposed.