127074-85-5

Upstream product

• 127074-91-3 2-(4-Piperidino-piperidino)-1-phenyl-ethanon 
• 532-27-4 1-chloroacetophenone 
• 96-09-3 styrene oxide 
• 4897-50-1 4-piperidinopiperidin 

Downstream Products

• 1269605-89-1 1-{1-Phenyl-2-[4-(piperidin-1-yl)piperidin-1-yl]ethyl}-4-(propan-2-yl)piperazine 
• 127074-92-4 4-(4-Nitrobenzoyloxy)-1-<2-(4-nitrobenzoyloxy)-2-phenylethyl>-piperidon-2 
• 127074-79-7 4-Hydroxy-1-(2-oxo-phenylethyl)-piperidon-2 
• 127074-81-1 1-(2-Oxo-2-phenylethyl)-2,4-piperidin-dion 
• 69914-21-2 1-(2-hydroxy-2-phenylethyl)-1,2-dihydropyridin-2-one 
• 127074-74-2 1-(2-Hydroxy-2-phenylethyl)-5,6-dihydro-pyridon-2 
• 127074-73-1 4-Hydroxy-1-(2-hydroxy-2-phenylethyl)-piperidon-2 
• 100-52-7 benzaldehyde 

Relevant academic research and scientific papers

Novel Ethanediamone Hepcidine Antagonists

The present invention relates to novel hepcidin antagonists of formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for treatment of disorders in iron metabolism, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias in connection with chronic inflammatory diseases (ACD: anaemia of chronic disease and AI: anaemia of inflammation).

Sodium mercury edetate dehydrogenation of N-aliphatic substituted 1,2,3,6-tetrahydropyridine derivatives

Hg(II)-edta dehydrogenation of N-aliphatic substituted Δ3-piperideine 1 leads to polymers. From 4 carrying a hydroxy neighbour group in the aliphatic side chain, it is possible to yield definite oxidation products - in dependence of nucleophiles present - mainly 4-substituted piperidone-2 derivatives 5 and 9-12. The oxidation of corresponding 4-hydroxy- (19) or 4-amino- (20, 21) piperidines gives the same spectrum of products. A mechanism for all the reactions is proposed.