127075-57-4Relevant academic research and scientific papers
Annulation by Sequential Doubla Michael Reaction; Synthesis of Decalones and Its Application to the Syntheses of ε-Cadinene, Khusitone and Khusilal
Hagiwara, Hisahiro,Akama, Tsutomu,Okano, Akihiro,Uda, Hisashi
, p. 2173 - 2184 (2007/10/02)
Reaction of kinetic enolates or the trimethylsilyl enol ethers of 1-acetylcyclohexenes with α,β-unsaturated carbonyl compounds affords 4-substituted 1-decalone derivatives under basic or Lewis acidic conditions.The reaction with acrylates of chiral alcohols has achieved 70percent diastereoselection.Application of these reactions has enabled syntheses of ε-cadinene, khusitone and khusial to be accomplished.
A Synthesis of (+/-)-Khusilal
Hagiwara, Hisahiro,Akama, Tsutomu,Uda, Hisashi
, p. 2067 - 2068 (2007/10/02)
(+/-)-Khusilal, a C14-terpenoid isolated from North Indian vetiver oil, has been synthesized from the decalone derivative prepared by a double Michael reaction.
