127106-04-1

Basic information

• Product Name: N-<2-methyl-2-(4-methylphenyl)-1-propylidene>isopropylamine
• CAS NO: 127106-04-1
• Molecular Weight: 203.327
• Mol File: 127106-04-1.mol

Chemical Properties

• CAS DataBase Reference: N-<2-methyl-2-(4-methylphenyl)-1-propylidene>isopropylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-<2-methyl-2-(4-methylphenyl)-1-propylidene>isopropylamine(127106-04-1)
• EPA Substance Registry System: N-<2-methyl-2-(4-methylphenyl)-1-propylidene>isopropylamine(127106-04-1)

Safety Data

• Hazardous Substances Data: 127106-04-1(Hazardous Substances Data)

Upstream product

• 62134-67-2 [2-Chloro-2-methyl-prop-(E)-ylidene]-isopropyl-amine 
• 108-88-3 toluene 

Relevant articles and documents

Α-ARYLATION OF ALDEHYDES VIA Α-CHLOROALDIMINES

α-Chloroaldimines are arylated at the α-position under Friedel-Crafts conditions via the presumptive intermediacy of α-imidoylcarbenium ions.Aluminium (III)chloride in arenes cleanly converted α-chloro-α-phenylaldimines into α-aryl-α-phenylaldimines.Aliphatic α-chloroaldimines could only be converted into the corresponding α-arylaldimines in low to moderate yields due to a lower reactivity and a competitive side reaction, i.e. dehydrochlorination into 1-aza-1,3-dienes. α-Bromo- and α-iodoaldimines were also evaluated under the given Friedel-Crafts conditions but the results appeared to be negative.The formation of all reaction products (i.e. α-arylaldimines, 1-aza-1,3-dienes and indolines) from the reaction of α-chloroaldimines with arenes in the presence of Lewis acids could be explained by the intermediacy of α-imidoylcarbenium ions, the chemistry of which is discussed to some extent.