1271111-26-2Relevant academic research and scientific papers
Transition-Metal-Free Oxidative Decarboxylative Cross Coupling of α,β-Unsaturated Carboxylic Acids with Cyclic Ethers under Air Conditions: Mild Synthesis of α-Oxyalkyl Ketones
Ji, Peng-Yi,Liu, Yu-Feng,Xu, Jing-Wen,Luo, Wei-Ping,Liu, Qiang,Guo, Can-Cheng
, p. 2965 - 2971 (2017)
A novel K2S2O8-promoted decarboxylative cross coupling of α,β-unsaturated carboxylic acids with cyclic ethers was developed under aerobic conditions. The present protocol, which includes C-C and C=O bond formation in one s
Method of decarboxylation oxidative coupling for [alpha], [beta]-unsaturated carboxylic acid and cyclic ether compound
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Paragraph 0070; 0108; 0109; 0110; 0111, (2017/08/27)
The invention discloses a method of decarboxylation oxidative coupling for [alpha], [beta]-unsaturated carboxylic acid and a cyclic ether compound. In the method, under an oxygen-containing atmosphere, the [alpha], [beta]-unsaturated carboxylic acid and t
Method for performing decarboxylated oxidative coupling on cinnamic acid derivatives and cyclic ethers
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Paragraph 0069; 0107; 0108; 0109; 0110, (2017/08/27)
The invention discloses a method for performing decarboxylated oxidative coupling on cinnamic acid derivatives and cyclic ethers. The method comprises the step of carrying out a one-pot reaction between the cinnamic acid derivatives and cyclic ethers in a
Asymmetric catalytic cycloetherification mediated by bifunctional organocatalysts
Asano, Keisuke,Matsubara, Seijiro
, p. 16711 - 16713 (2011/12/03)
Oxacyclic structures such as tetrahydrofuran (THF) rings are commonly found in many bioactive compounds, and this has led to several efforts toward their stereoselective syntheses. However, the process of catalytic asymmetric cycloetherification for their straightforward synthesis has remained a challenge. In this study, we demonstrate a novel asymmetric synthesis method for THF via the catalytic cycloetherification of ε-hydroxy-α,β- unsaturated ketones mediated by cinchona-alkaloid-thiourea-based bifunctional organocatalysts. This catalytic process represents a highly practical cycloetherification method that provides excellent enantioselectivities, even with low catalyst loadings at ambient temperature.
