1271332-59-2

Upstream product

• 76-83-5 trityl chloride 
• 583843-85-0 (R)-1-((3aR,5R,6R,6aR)-6-Allyl-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-ethane-1,2-diol 

Downstream Products

• 1271332-66-1 (R)-1-((3aR,5R,6R,6aR)-6-(benzyloxy)-6-(2-hydroxyethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)-2-(trityloxy)ethanol 
• 1271332-69-4 (3aR,5R,6R,6aR)-6-(benzyloxy)-5-((R)-1-(benzyloxy)-2-(trityloxy)ethyl)-6-(2-benzyloxyethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole 
• 1271332-71-8 (R)-2-(benzyloxy)-2-((3aR,5R,6R,6aR)-6-(benzyloxy)-6-(2-(benzyloxy)ethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethanol 
• 1271332-74-1 (R)-2-(benzyloxy)-2-((3aR,5R,6R,6aR)-6-(benzyloxy)-6-(2-(benzyloxy)ethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethyl methanesulfonate 
• 1271332-77-4 (3aR,5R,6R,6aR)-5-((R)-2-azido-1-(benzyloxy)ethyl)-6-(benzyloxy)-6-(2-(benzyloxy)ethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole 
• 1271332-80-9 (2R,3R,4R)-1-azido-2,4,6-tris(benzyloxy)-4-formylhexan-3-yl formate 
• 1271332-83-2 (2R,3R,4R)-5-azido-2,4-bis(benzyloxy)-2-(2-(benzyloxy)ethyl)pentane-1,3-diol 
• 1271332-86-5 (2R,3R,4R)-1-azido-2,4,6-tris(benzyloxy)-4-(trityloxymethyl)hexan-3-ol 
• 1271332-89-8 (2R,3R,4R)-1-azido-2,3,4,6-tetra(benzyloxy)-4-(trityloxymethyl)hexane 
• 1271332-93-4 (2R,3R,4R)-5-azido-2,3,4-tris(benzyloxy)-2-(2-(benzyloxy)ethyl)pentan-1-ol 
• 1271332-96-7 (2R,3R,4R)-5-azido-2,3,4-tris(benzyloxy)-2-(2-(benzyloxy)ethyl)pentyl methanesulfonate 
• 1271332-99-0 (2R,3R,4R)-2,3,4-tris(benzyloxy)-2-(2-(benzyloxy)ethyl)-5-(tert-butoxycarbonylamino)pentyl methanesulfonate 
• 1271333-02-8 (3S,4R,5R)-tert-butyl 3,4,5-tris(benzyloxy)-3-(2-(benzyloxy)ethyl)piperidine-1-carboxylate 

Relevant academic research and scientific papers

(3S,4R,5R)-3-(2-Hydroxyethyl)piperidine-3,4,5-triol as an isofagomine analogue: Synthesis and glycosidase inhibition study

The synthesis of (3S,4R,5R)-3-(2-hydroxyethyl)piperidine-3,4,5-triol 10 has been described from d-glucose. The base promoted cyclization for the construction of the piperdine framework is the key step of the synthesis.