127182-48-3

Upstream product

• 113826-06-5 (R)-glycidyl tosylate 

Downstream Products

• 1429334-05-3 4-[4-{(R)-2-hydroxy-3-azidopropylamino}phenyl]morpholin-3-one 
• 942902-57-0 methyl (2S,5S,6S)-1-((R)-3-azido-2-hydroxypropyl)-6-(4-bromophenyl)-5-methylpiperidine-2-carboxylate 
• 936445-26-0 (3R,6S,7S,9aS)-3-(azidomethyl)-6-(3-bromophenyl)-7-methyl-hexahydropyrido[2,1-c][1,4]oxazin-1(6H)-one 
• 936444-99-4 (3R,6R,7R,9aS)-3-(azidomethyl)-6-(4-bromophenyl)-7-methyl-hexahydropyrido[2,1-c][1,4]oxazin-1(6H)-one 
• 936445-13-5 (3R,6R,7R,9aS)-3-(azidomethyl)-6-(3-bromophenyl)-7-methyl-hexahydropyrido[2,1-c][1,4]oxazin-1(6H)-one 

Relevant academic research and scientific papers

Nucleophilic reaction of glycidol tosylate and the corresponding cyclic sulfate with various nucleophiles: A comparative study

The nucleophilic reaction of glycidol tosylate and the corresponding cyclic sulfate tosylate have been carried out with a number of nucleophiles to study the possible attack of nucleophiles at C1, C2 or C3 positions. The regioselectivity and reactivity of both the substrates i.e. epoxide tosylate 1 and the corresponding cyclic sulfate 2 have been compared and established that under similar conditions cyclic sulfate counterpart shows better regioselectivity and better reactivity than the corresponding epoxide.

Chiral glycidyl azides as synthetic intermediates to optically active compounds

Chiral glycidyl azides, such as (2S)-glycidyl azide, are prepared, and they are useful as intermediates to prepare optically active compounds, particularly optically active, anti-bacterial oxazolidinones.