127188-33-4 Usage
Uses
Used in Pharmaceutical Chemistry:
4-BOC-1-(6-METHYL-2-PYRIDYL)PIPERAZINE is used as a precursor compound for the synthesis of various bioactive molecules, particularly those with potential applications in the treatment of central nervous system disorders. Its BOC protecting group allows for selective reactions, facilitating the creation of complex molecular structures with desired pharmacological properties.
Used in Organic Synthesis:
In the field of organic synthesis, 4-BOC-1-(6-METHYL-2-PYRIDYL)PIPERAZINE is employed as a versatile intermediate. The presence of the BOC group enables chemists to carry out reactions without affecting the amine functionality, which can be later deprotected to reveal the free amine group, allowing for further reactions and the formation of diverse organic compounds.
Used in Drug Development:
4-BOC-1-(6-METHYL-2-PYRIDYL)PIPERAZINE is utilized as a key intermediate in the development of new drugs. Its reactivity and structural features make it suitable for the creation of pharmaceutical agents that can modulate biological targets, potentially leading to the discovery of novel therapeutics for various diseases and conditions.
Used in Research and Development:
In the research and development sector, 4-BOC-1-(6-METHYL-2-PYRIDYL)PIPERAZINE serves as a valuable tool for exploring new chemical reactions and understanding the properties of related compounds. Its use in academic and industrial research can lead to advancements in the fields of medicinal chemistry and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 127188-33-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,1,8 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 127188-33:
(8*1)+(7*2)+(6*7)+(5*1)+(4*8)+(3*8)+(2*3)+(1*3)=134
134 % 10 = 4
So 127188-33-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H23N3O2/c1-12-6-5-7-13(16-12)17-8-10-18(11-9-17)14(19)20-15(2,3)4/h5-7H,8-11H2,1-4H3
127188-33-4Relevant academic research and scientific papers
POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS
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Page/Page column 92, (2018/07/29)
The present invention is related to a pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent and a compound represented by the following structural formula: The present invention is also related a method of treating a subject with a disease which can be ameliorated by inhibition of poly(ADP-ribose)polymerase (PARP). The definitions of the variables are provided herein.
Discovery of bishomo(hetero)arylpiperazines as novel multifunctional ligands targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors
Butini, Stefania,Campiani, Giuseppe,Franceschini, Silvia,Trotta, Francesco,Kumar, Vinod,Guarino, Egeria,Borrelli, Giuseppe,Fiorini, Isabella,Novellino, Ettore,Fattorusso, Caterina,Persico, Marco,Orteca, Nausicaa,Sandager-Nielsen, Karin,Jacobsen, Thomas Amos,Madsen, Kim,Scheel-Kruger, Jorgen,Gemma, Sandra
supporting information; experimental part, p. 4803 - 4807 (2010/10/03)
As a continuation of our efforts to develop innovative ligands for D 3, 5-HT1A, and 5-HT2A receptors with low propensity to block hERG channels, we propose a series bishetero(homo) arylpiperazines 5a-m as novel and potent multifunctional ligands characterized by low occupancy at D2 and 5-HT2C receptors.
Novel Aryl Piperazine Derivatives With Medical Utility
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Page/Page column 35, (2009/10/01)
This invention provides novel aryl piperazine derivatives having medical utility, in particular as modulators of dopamine and serotonin receptors, preferably the D3, D2-like and 5-HT2 receptor subtypes, and in particular u
