127199-44-4

Basic information

• Product Name: Carbamic acid, (7R)-5-azaspiro[2.4]hept-7-yl-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, (7R)-5-azaspiro[2.4]hept-7-yl-, 1,1-dimethylethyl ester (9CI);(R)-tert-butyl 5-azaspiro[2.4]heptan-7-ylcarbamate;N-(7R)-5-Azaspiro[2.4]hept-7-yl-carbamic acid 1,1-dimethylethyl ester;tert-butyl N-[(7R)-5-azaspiro[2.4]heptan-7-yl]carbamate;(R)-(5-Aza-spiro[2.4]hept-7-yl)-carbamic acid tert-butyl ester;Sitafloxacin Impurity 13
• CAS NO: 127199-44-4
• Molecular Formula: C11H20N2O2
• Molecular Weight: 212.2887
• Product Categories: N-BOC
• Mol File: 127199-44-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 329.029 °C at 760 mmHg
• Flash Point: 152.791 °C
• Appearance: /
• Density: 1.09±0.1 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 12.39±0.40(Predicted)
• CAS DataBase Reference: Carbamic acid, (7R)-5-azaspiro[2.4]hept-7-yl-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (7R)-5-azaspiro[2.4]hept-7-yl-, 1,1-dimethylethyl ester (9CI)(127199-44-4)
• EPA Substance Registry System: Carbamic acid, (7R)-5-azaspiro[2.4]hept-7-yl-, 1,1-dimethylethyl ester (9CI)(127199-44-4)

Safety Data

• Hazardous Substances Data: 127199-44-4(Hazardous Substances Data)

Usage

General Description

Carbamic acid, (7R)-5-azaspiro[2.4]hept-7-yl-, 1,1-dimethylethyl ester (9CI) is a highly specific chemical compound with a complex structure. As implied by its name, the structure includes a carbamic acid component, a spirocyclic moiety, essential for giving it unique chemical properties. The attachment of a 1,1-dimethylethyl ester side-chain also contributes to its overall structural complexity. However, the detailed information regarding the exact properties, uses, toxicology, or potential applications in various sectors of this chemical is not explicitly mentioned, which suggests that this compound may not be typical or widely studied.

Upstream product

• 1432056-70-6 C₁₈H₂₆N₂O₂ 
• 127199-39-7 7-(R)-amino-5-<1(R)-phenylethyl>-4-oxo-5-azaspiro<2.4>heptane 
• 127199-40-0 7-(R)-amino-5-<1(R)-phenylethyl>-5-azaspiro<2.4>heptane 
• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 127199-43-3 7(R)-<(tert-butoxycarbonyl)amino>-5-<1(R)-phenylethyl>-5-azaspiro<2.4>heptane 

Downstream Products

• 127199-06-8 7-((R)-7-Amino-5-aza-spiro[2.4]hept-5-yl)-8-chloro-6-fluoro-1-(2-fluoro-cyclopropyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 
• 127199-06-8 7-((R)-7-Amino-5-aza-spiro[2.4]hept-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluoro-cyclopropyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 
• 127199-06-8 7-((R)-7-Amino-5-aza-spiro[2.4]hept-5-yl)-8-chloro-6-fluoro-1-((1S,2R)-2-fluoro-cyclopropyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 

Relevant articles and documents

Preparation method of sitafloxacin hydrate

The invention provides a preparation method of a sitafloxacin hydrate. The preparation method takes a compound II as a raw material, debenzylation, substitution, chlorination and removal of t-butyloxycarboryl are sequentially carried out, and finally the sitafloxacin hydrate is obtained. The preparation method provided by the invention has the advantages that use of hydrogen and an autoclave is avoided, technological operation is greatly simplified, and hidden danger is also eliminated; and reaction in each technological step is rapid, no side reaction is generated, and separation and purification are simple and rapid, so that the preparation method provided by the invention not only has high yield, more importantly, the preparation method also has the advantages of environment friendliness, simple technology and low cost, and industrial large-scale mass production requirement can be met.