127200-84-4Relevant academic research and scientific papers
Highly Stereocontrolled Synthesis of the Key Intermediate of 1β-Methylcarbapenem Antibiotic via Intramolecular Nitrone 1,3-Dipolar Cycloaddition
Ihara, Masataka,Takahashi, Masanobu,Fukumoto, Keiichiro,Kametani, Tetsuji
, p. 9 - 10 (1988)
The key synthetic intermediate of 1β-methylcarbapenem antibiotic, (-)-(3S,4R)-3--4-azetidin-2-one (2), was synthesized from (R)-methyl 3-hydroxy-2-methylpropionate with high stereoselectivity vi
