Journal of the Chemical Society. Chemical communications p. 9 - 10 (1988)
Update date:2022-07-29
Topics:
Ihara, Masataka
Takahashi, Masanobu
Fukumoto, Keiichiro
Kametani, Tetsuji
The key synthetic intermediate of 1β-methylcarbapenem antibiotic, (-)-(3S,4R)-3-<(1R)-1-t-butyldimethylsiloxyethyl>-4-<(2R)-2-(1-hydroxypropyl)>azetidin-2-one (2), was synthesized from (R)-methyl 3-hydroxy-2-methylpropionate with high stereoselectivity vi
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