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1272003-83-4

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1272003-83-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1272003-83-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,7,2,0,0 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1272003-83:
(9*1)+(8*2)+(7*7)+(6*2)+(5*0)+(4*0)+(3*3)+(2*8)+(1*3)=114
114 % 10 = 4
So 1272003-83-4 is a valid CAS Registry Number.

1272003-83-4Downstream Products

1272003-83-4Relevant academic research and scientific papers

Design, synthesis and biological evaluation of new thalidomide analogues as TNF-α and IL-6 production inhibitors

Chaulet, Charlotte,Croix, Cécile,Alagille, David,Normand, Sylvain,Delwail, Adriana,Favot, Laure,Lecron, Jean-Claude,Viaud-Massuard, Marie-Claude

, p. 1019 - 1022 (2011/03/21)

Several thalidomide analogues were synthesized and compared to thalidomide and its more active analogue, lenalidomide, for their ability to inhibit the production of the pro-inflammatory cytokine tumour necrosis factor (TNF)-α and interleukin (IL)-6 by LPS-activated peripheral blood mononuclear cells (PBMCs). Among these compounds, two analogues containing sulfonyl group displayed interesting downregulation of TNF-α and IL-6 production.

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