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1272004-17-7

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1272004-17-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1272004-17-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,7,2,0,0 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1272004-17:
(9*1)+(8*2)+(7*7)+(6*2)+(5*0)+(4*0)+(3*4)+(2*1)+(1*7)=107
107 % 10 = 7
So 1272004-17-7 is a valid CAS Registry Number.

1272004-17-7Relevant academic research and scientific papers

Design, synthesis and biological evaluation of new thalidomide analogues as TNF-α and IL-6 production inhibitors

Chaulet, Charlotte,Croix, Cécile,Alagille, David,Normand, Sylvain,Delwail, Adriana,Favot, Laure,Lecron, Jean-Claude,Viaud-Massuard, Marie-Claude

, p. 1019 - 1022 (2011)

Several thalidomide analogues were synthesized and compared to thalidomide and its more active analogue, lenalidomide, for their ability to inhibit the production of the pro-inflammatory cytokine tumour necrosis factor (TNF)-α and interleukin (IL)-6 by LPS-activated peripheral blood mononuclear cells (PBMCs). Among these compounds, two analogues containing sulfonyl group displayed interesting downregulation of TNF-α and IL-6 production.

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