127223-28-3 Usage
Isopropylidene group
A secondary alcohol group consisting of a hydroxyl group attached to a secondary carbon, which is part of a three-carbon chain with a quaternary carbon in the middle.
Hydroxy group
A functional group consisting of an oxygen atom bonded to a hydrogen atom (-OH), which can form hydrogen bonds and participate in various chemical reactions.
Ethyldinyl group
A two-carbon chain with a double bond between the carbons, which can undergo addition reactions and serve as a site for further functionalization.
Tetrahydrofuran ring
A five-membered cyclic ether with four carbon atoms and one oxygen atom, which provides a stable and rigid structure for the compound.
Organic Chemistry
1,2-O-isopropylidene-3-S-hydroxy-4-R-ethyldinyl tetrahydrofuran can be used as a building block for the synthesis of other organic compounds, allowing for the creation of complex molecules with various functional groups.
Pharmaceutical Research
The compound may have potential biological activity, which could make it a valuable candidate for drug development or as an intermediate in the synthesis of pharmaceuticals.
Biological Activity
Further studies are needed to fully understand the properties and potential uses of 1,2-O-isopropylidene-3-S-hydroxy-4-R-ethyldinyl tetrahydrofuran, including its interactions with biological systems and potential therapeutic applications.
Synthesis Optimization
Research into the synthesis of the compound may lead to more efficient and cost-effective methods, making it more accessible for use in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 127223-28-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,2,2 and 3 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 127223-28:
(8*1)+(7*2)+(6*7)+(5*2)+(4*2)+(3*3)+(2*2)+(1*8)=103
103 % 10 = 3
So 127223-28-3 is a valid CAS Registry Number.
127223-28-3Relevant academic research and scientific papers
Construction of key building blocks towards the synthesis of cortistatins
Indu, Satrajit,Kaliappan, Krishna P.,Telore, Rahul D.
, p. 2432 - 2446 (2020/04/22)
This work reports the construction of key building blocks towards the synthesis of cortistatins; a family of steroidal alkaloids. Cortistatin A, being a primary target due to its superior biological properties over other congeners, has been prepared by two different synthetic routes. Synthesis of the precursor to the heavily substituted A-ring starting from d-glucose and construction of the DE-ring junction employing a Hajos-Parrish ketone as a chiral pool have been demonstrated. Efforts are underway to assemble these key fragments and build towards the total synthesis of cortistatin A.
Radical Cyclization in Stereospecific Introduction of Chirality at "Off Template Site" of 1,2-O-Isopropylidene-α-D-xylo-hexofuranose
Rao, A. V. Rama,Yadav, J. S.,Rao, C. Srinivas,Chandrasekhar, S.
, p. 1211 - 1213 (2007/10/02)
Bromoacetals derived from 5,6-dideoxy-1,2-O-isopropylidene-α-D-xylo-hex-5-ynofuranose (9) undergo facile free radical cyclization leading to the formation of olefinic acetals which are chemically manipulated to introduce either of the chiralities at C-5 of α-D-hexofuranose.
CARBOHYDRATES AS A PRACTICAL SOURCE OF CHIRAL POLYHYDROXY ACETYLENES
Yadav, J.S.,Chander, Madhavi C.,Rao, C. Srinivas
, p. 5455 - 5458 (2007/10/02)
Syntheses of chiral polyhydroxy propargyl alcohols by employig double elimination of β-alkoxy chlorides with strong bases have been described.
