127223-88-5

Basic information

• Product Name: 3-Buten-2-one, 1,1,1-trifluoro-4-(methylamino)-, (3Z)-
• CAS NO: 127223-88-5
• Molecular Formula: C5H6F3NO
• Mol File: 127223-88-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Buten-2-one, 1,1,1-trifluoro-4-(methylamino)-, (3Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Buten-2-one, 1,1,1-trifluoro-4-(methylamino)-, (3Z)-(127223-88-5)
• EPA Substance Registry System: 3-Buten-2-one, 1,1,1-trifluoro-4-(methylamino)-, (3Z)-(127223-88-5)

Safety Data

• Hazardous Substances Data: 127223-88-5(Hazardous Substances Data)

Upstream product

• 59938-06-6 (E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one 
• 74-89-5 methylamine 
• 127223-85-2 ethyl β-(trifluoroacetyl)vinyl sulfide 
• 120417-45-0 4-amino-1,1,1-trifluoro-3-buten-2-one 

Relevant articles and documents

Halogenation of β-alkoxyvinyl polyhaloalkyl ketones: A convenient route for the synthesis of α-chloro- or α-bromo-β-alkoxyvinyl polyhaloalkyl ketones

A number of α-chloro- and α-bromo-β-alkoxyvinyl polyhaloalkyl ketones 4 and 5 were synthesized in high yields by halogenation of β-alkoxyvinyl polyhaloalkyl ketones 1 with chlorine or bromine and further dehydrohalogenation of dihalo-intermediates 2 and 3 with pyridine. The Z configuration of ketones 4 and 5 was deduced from X-ray analysis and NMR spectra. Some typical nucleophilic reactions of the title compounds 4 and 5 with amines were carried out to check their reactivity.