1272319-73-9Relevant articles and documents
Synthesis of the key intermediate of ramelteon
Yu, Shan Bao,Liu, Hao Min,Luo, Yu,Lu, Wei
, p. 264 - 267 (2012/01/05)
Asymmetric conjugated addition of allylcopper reagents derived from an allyl Grignard reagent and CuBr·Me2S to chiral α,β-unsaturated N-acyl oxazolidinones has been achieved. The synthetic procedure was applied to the preparation of the key intermediate of the novel nonbenzodiazepine hypnotic drug, ramelteon.