127234-68-8Relevant articles and documents
Altering pyridinone N-substituents to optimise activity as potential prodrugs for Alzheimer's disease
Scott, Lauren E.,Page, Brent D. G.,Patrick, Brian O.,Orvig, Chris
, p. 6364 - 6367 (2008)
Selective design modifications of specifically substituted 3-hydroxy-4(1H)-pyridinones show possibly advantageous ring freedom while maintaining metal-binding ability and antioxidant capacity, moving toward an efficient potential treatment for Alzheimer's disease.
Monobactam hydrazide derivatives
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, (2008/06/13)
Compounds having the formula I and pharmaceutically acceptable salts thereof which possess antibacterial activity. Rs is a substituted hydroxy pyridone of the formulae: II and III wherein Y1 is CH2X; COOR6; CONR7R8; OH; OCH2R9; CHF2; CHO; CH=N-OR10; CH=CH-R11; CN; CH=N-NHR12, and Y2 is hydrogen; COOH; CONH2; CN; CSNH2; COO lower alkyl; CONR7/R8