127235-42-1

Basic information

• Product Name: β-5-(2''-thienyl)-2'-deoxy-3',5'-di-O-toluoyluridine
• Synonyms: β-5-(2''-thienyl)-2'-deoxy-3',5'-di-O-toluoyluridine
• CAS NO: 127235-42-1
• Molecular Weight: 546.601
• Mol File: 127235-42-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: β-5-(2''-thienyl)-2'-deoxy-3',5'-di-O-toluoyluridine(CAS DataBase Reference)
• NIST Chemistry Reference: β-5-(2''-thienyl)-2'-deoxy-3',5'-di-O-toluoyluridine(127235-42-1)
• EPA Substance Registry System: β-5-(2''-thienyl)-2'-deoxy-3',5'-di-O-toluoyluridine(127235-42-1)

Safety Data

• Hazardous Substances Data: 127235-42-1(Hazardous Substances Data)

Upstream product

• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 
• 54663-78-4 tributyl(thien-2-yl)stannane 
• 31356-86-2 1-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-5-iodouracil 
• 37496-13-2 2-(trimethylstannyl)thiophene 

Downstream Products

• 134333-72-5 5-(5-chlorothien-2-yl)-2'-deoxyuridine 
• 134333-70-3 5-(5-bromothien-2-yl)-2'-deoxyuridine 
• 177779-40-7 Heptanedioic acid benzyl ester (2R,3S,5R)-5-(2,4-dioxo-5-thiophen-2-yl-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 
• 177779-39-4 Hexanedioic acid benzyl ester (2R,3S,5R)-5-(2,4-dioxo-5-thiophen-2-yl-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 
• 177779-38-3 Pentanedioic acid benzyl ester (2R,3S,5R)-5-(2,4-dioxo-5-thiophen-2-yl-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 

Relevant articles and documents

Synthesis and in vitro antileishmanial activity of 5-substituted-2′- deoxyuridine derivatives

We report herein the synthesis and the in vitro antileishmanial evaluation of 5-substituted-2′-deoxyuridine nucleosides. The most active compound against Leishmania donovani promastigotes was Thia-dU (3a) with an IC 50 = 3 μM. This compound exh

5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-Chlorothien-2-yl)-2'-deoxyuridine Are Equipotent to (E)-5-(2-Bromovinyl)-2'-deoxyuridine in the Inhibition of Herpes Simplex Virus Type I Replication

2'-Deoxyuridines with a five-membered heterocyclic substituent in the 5-position were synthesized by palladium-catalyzed coupling reactions of 5-iodo-2'-deoxyuridine with the activated heteroaromatics.Further modification of the compound with the 5-thien-