31356-86-2

Upstream product

• 38953-72-9 5-iodo-2,4-bis-O-trimethylsilyluracil 
• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 
• 4449-38-1 2'-deoxy-3',5'-di-O-(4-methylbenzoyl)uridine 
• 951-78-0 2'-deoxyuridine 
• 106-43-4 para-chlorotoluene 
• 54-42-2 5-Iodo-2'-deoxyuridine 
• 874-60-2 4-methyl-benzoyl chloride 

Downstream Products

• 77875-94-6 C₃₄H₃₆N₂O₉ 
• 77875-86-6 C₂₉H₂₈N₂O₇ 
• 77875-87-7 C₃₀H₃₀N₂O₇ 
• 77875-89-9 C₃₂H₃₄N₂O₇ 
• 77875-93-5 C₃₃H₃₄N₂O₉ 
• 153865-91-9 5-<3-hydroxy-3-(p-tolyl)prop-1-ynyl>-3',5'-di-O-(p-toluoyl)-2'-deoxyuridine 
• 153865-92-0 5-<3-hydroxy-3-(p-methoxyphenyl)prop-1-ynyl>-3',5'-di-O-(p-toluoyl)-2'-deoxyuridine 
• 55520-65-5 3',5'-di-O-p-toluoyl-5-ethenyl-2'-deoxyuridine 
• 125654-44-6 C₃₃H₃₀N₂O₇ 
• 127235-40-9 5-furan-2-yl-1-(3,5-di-O-toluyl-β-D-2-deoxyribofuranos-1-yl)uracil 
• 127235-42-1 β-5-(2''-thienyl)-2'-deoxy-3',5'-di-O-toluoyluridine 
• 77882-22-5 C₃₇H₃₄N₂O₉ 
• 77875-88-8 5-Hexynyl-3',5'-di-O-p-toluyl-2'-deoxyuridine 
• 153865-90-8 5-(3-hydroxy-3-phenylprop-1-ynyl)-3',5'-di-O-(p-toluoyl)-2'-deoxyuridine 

Relevant academic research and scientific papers

Furan decorated nucleoside analogues as fluorescent probes: synthesis, photophysical evaluation, and site-specific incorporation

The synthesis and photophysical evaluation of modified nucleoside analogues in which a five-membered heterocycle (furan, thiophene, oxazole, and thiazole) is attached to the 5-position of 2′-deoxyuridine are reported. The furan-containing derivative is id

Synthesis of carbohydrate-conjugated dT analogues using 'click chemistry'

A new type furo[2,3-d]pyrimidine nucleoside conjugated with various carbohydrates was synthesized using Sonogashira coupling and 'click chemistry'. In the subsequent deprotection of the 4-toluoyl and acetyl groups with catalytic sodium methoxide in methan

5-Propynylamino α-deoxyuridine promotes DNA duplex stabilization of anionic and neutral but not cationic α-oligonucleotides

Incorporation of 5-propynylamino and 5-propynyl α-2′-deoxyuridine into α-oligonucleotides (α-ON) allows high-affinity targeting of complementary DNA for α-ON with anionic and neutral backbone but not for cationic α-ON, revealing clues on the role of the a

Simple fluorescent pyrimidine analogues detect the presence of DNA abasic sites

A family of simple pyrimidine analogues has been synthesized, and their photophysical properties have been investigated. The most responsive of the family was incorporated in DNA. This isosteric fluorescent DNA analogue monitors denaturation of a DNA dupl

Base analogues

Nucleotide or base analogues having structure (3) or (4) wherein X═O or NH or S and each R6is independently H or alkyl or alkenyl or alkoxy or aryl or a reporter moiety.

Nucleoside derivatives

A nucleoside derivative of formula (1), characterized in that: Y is H or OH or a protected hydroxy group; X is H, a phosphonate group or a phosphoramidite group of formula (II), where R1 and R2 are the same or different, and are selected from alkyl and substituted alkyl, which may be branched or unbranched; and Q is a phosphate protecting group; Z is H, a phosphate or triphosphate group or hydroxy protecting group; X' is a C1-15 alkyl group which may be branched or unbranched; R is an amino protecting group or a fluorophore, or other non-radioactive detectable marker; or the group Y'NHA, where Y' is an alkyl (C1-40) carbonyl group which may be branched or unbranched, and A is an amino protecting group or a fluorophore or other non-radioactive detectable marker. Methods for the synthesis and sequencing of polynucleotides utilizing compounds of formula (I).

5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-Chlorothien-2-yl)-2'-deoxyuridine Are Equipotent to (E)-5-(2-Bromovinyl)-2'-deoxyuridine in the Inhibition of Herpes Simplex Virus Type I Replication

2'-Deoxyuridines with a five-membered heterocyclic substituent in the 5-position were synthesized by palladium-catalyzed coupling reactions of 5-iodo-2'-deoxyuridine with the activated heteroaromatics.Further modification of the compound with the 5-thien-

Nucleic acid related compounds. 38. Smooth and high-yield iodination and chlorination at C-5 of uracil bases and p-toluyl-protected nucleosides

Treatment of uracil bases and protected nucleosides with iodine monochloride (ICl) gave the corresponding 5-iodouracil products in over 95percent purified yields.Analogously facile chlorination was effected with iodobenzene dichloride (PhICl2).Protection of the nucleosides as p-toluyl esters provided reactants that were soluble in organic solvents and crystallized readily in high yields.