127236-58-2Relevant academic research and scientific papers
Synthesis of naphthyl-substituted terminal olefins via Pd-Catalyzed one-pot coupling of acetylnaphthalene, N-Tosylhydrazide with aryl halide
Shen, Xu,Liu, Ping,Liu, Yan,Dai, Bin
supporting information, p. 6558 - 6563 (2017/10/17)
In this study, a one-pot two-step Pd-catalyzed reductive eliminate between acetyl naphthalene derivatives, tosylhydrazide, and aryl halide, affording substituted 1(or 2)-(1-phenylvinyl)naphthalene in moderate-to-excellent yields, was reported. Notably, so
Traceless directing group mediated branched selective alkenylation of unbiased arenes
Agasti, Soumitra,Dey, Aniruddha,Maiti, Debabrata
supporting information, p. 12191 - 12194 (2016/10/21)
Owing to the synthetic importance of branched olefinated products, we report palladium catalyzed formation of branched olefins facilitated by a C-H activation based protocol. This involves selective insertion of olefins and subsequent decarboxylation using a completely unbiased benzene ring as the starting precursor. The significance of the protocol has been further highlighted by exhibition of functionality tolerance along with a late-stage modification of the branched olefinated products leading to the formation of other functionalized molecules.
Branched Arylalkenes from Cinnamates: Selectivity Inversion in Heck Reactions by Carboxylates as Deciduous Directing Groups
Tang, Jie,Hackenberger, Dagmar,Goossen, Lukas J.
supporting information, p. 11296 - 11299 (2016/10/13)
A decarboxylative Mizoroki–Heck coupling of aryl halides with cinnamic acids has been developed in which the carboxylate group directs the arylation into its β-position before being tracelessly removed through protodecarboxylation. In the presence of a copper/palladium catalyst, both electron-rich and electron-deficient aryl bromides and chlorides bearing numerous functionalities were successfully coupled with broadly available cinnamates, with selective formation of 1,1-disubstituted alkenes. This reaction concept, in which the carboxylate acts as a deciduous directing group, ideally complements traditional 1,2-selective Heck reactions of styrenes.
A ligand free and room temperature protocol for Pd-catalyzed kumada-corriu couplings of unactivated alkenyl phosphates
Gauthier, Delphine,Beckendorf, Stephan,Gogsig, Thomas M.,Lindhardt, Anders T.,Skrydstrup, Troels
supporting information; experimental part, p. 3536 - 3539 (2009/09/30)
Kumada - Corriu cross-couplings of nonactivated cyclic and acyclic vinyl phosphates with aryl magnesium reagents afforded a series of 1,1-disubtituted alkenes in good yields for most cases when the reactions were performed at room temperature with the sim
PtBr2-catalyzed consecutive enyne metathesis-aromatization of 1-(1-methoxy-but-3-enyl)-2-(1-alkynyl)benzenes: Dual role of the Pt catalyst
Bajracharya, Gan B.,Nakamura, Itaru,Yamamoto, Yoshinori
, p. 892 - 897 (2007/10/03)
(Chemical Equation Presented) 1,7-Enynes 1, connected through an aromatic ring and bearing a leaving methoxy group at the 4-position, underwent the PtBr2-catalyzed enyne metathesis followed by aromatization in one pot to afford vinyl naphthalen
