127290-82-8

Basic information

• Product Name: Cbz-L-Gln-Gly-Gly
• CAS NO: 127290-82-8
• Molecular Weight: 394.384
• Mol File: 127290-82-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cbz-L-Gln-Gly-Gly(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-L-Gln-Gly-Gly(127290-82-8)
• EPA Substance Registry System: Cbz-L-Gln-Gly-Gly(127290-82-8)

Safety Data

• Hazardous Substances Data: 127290-82-8(Hazardous Substances Data)

Upstream product

• 556-50-3 glycylglycine 
• 7763-16-8 N²-benzyloxycarbonyl-L-glutamine-(4-nitro-phenyl ester) 
• 6610-42-0 α-N-carbobenzyloxy-L-glutamine-glycine 
• 56-40-6 glycine 
• 2650-64-8 Cbz-L-Gln 

Relevant articles and documents

Peptide coupling of unprotected amino acids through in situ p-nitrophenyl ester formation

Several series of dipeptides and tripeptides were prepared via an activation-coupling method involving the in situ formation of a p-nitrophenyl ester of an (N-protected) amino acid, followed by coupling with an unprotected amino acid in partially aqueous solutions. The resulting peptide is easily isolated by precipitation. In general, the yields obtained are good to excellent and racemization is minimal. This method is particularly advantageous with respect to its simplicity and lack of obligatory side chain protection/deprotection steps.