127294-20-6

Basic information

• Product Name: 2-(4-methoxyphenyl)ethyl phenyl ether
• Synonyms: 2-(4-methoxyphenyl)ethyl phenyl ether
• CAS NO: 127294-20-6
• Molecular Weight: 228.291
• Mol File: 127294-20-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxyphenyl)ethyl phenyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)ethyl phenyl ether(127294-20-6)
• EPA Substance Registry System: 2-(4-methoxyphenyl)ethyl phenyl ether(127294-20-6)

Safety Data

• Hazardous Substances Data: 127294-20-6(Hazardous Substances Data)

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 1408168-74-0 potassium (2-phenyloxyethyl)trifluoroboride 
• 4249-72-3 2-phenoxy-1-phenylethanol 
• 19513-79-2 2-phenoxy-1-p-tolylethanone 
• 19513-78-1 1-(4-methoxy-phenyl)-2-phenoxy-ethanone 
• 721-04-0 2-phenoxy-1-phenylethanone 
• 1173371-76-0 1-methyl-4-(2-phenoxyethyl)benzene 
• 29509-35-1 1-methoxy-2-phenoxy-1-phenylethane 
• 6640-19-3 2-phenoxy-1-phenylpropan-1-one 
• 930-68-7 cyclohexenone 
• 702-23-8 2-(4-Methoxyphenyl)ethanol 
• 29509-29-3 1-(4-methoxyphenyl)-2-phenoxyethan-1-ol 
• 589-10-6 phenoxyethyl bromide 
• 14425-64-0 4-methoxyphenethyl bromide 

Downstream Products

• 123-11-5 4-methoxy-benzaldehyde 
• 127294-22-8 2-acetoxy-2-(4-methoxyphenyl)ethyl phenyl ether 
• 19513-78-1 1-(4-methoxy-phenyl)-2-phenoxy-ethanone 

Relevant articles and documents

The selective hydrogenolysis of C-O bonds in lignin model compounds by Pd-Ni bimetallic nanoparticles in ionic liquids

β-O-4 and α-O-4 linkages can be selectively cleaved by Pd-Ni bimetallic nanoparticles in ionic liquids using hydrogen gas as the hydrogen donor under ambient pressure and neutral conditions. No hydrogenation of the benzene ring takes place in the catalytic system. An obvious improvement in activity is found compared with single nickel and palladium catalysts based on the results of experiments and characterization. After the reaction, the catalytic system still remains in the reactor by simple extraction, which can be reused without further treatment.

Metal-Free I2-Catalyzed Highly Selective Dehydrogenative Coupling of Alcohols and Cyclohexenones

The I2 catalyzed highly selective oxidative condensation of cyclohexenones and alcohols for the synthesis of aryl alkyl ethers has been described. DMSO is employed as the mild terminal oxidant. This novel methodology offers a metal-free reaction condition, operational simplicity and broad substrate scope to afford valuable products from inexpensive reagents. Various meta-substituted aromatic ethers which are hardly synthesized from the reported methods requiring meta-substituted phenols, are efficiently prepared by the present protocol.

ONE ELECTRON OXIDATION OF BENZYL AND 2-PHENYLETHYL PHENYL ETHERS. THE FATE OF THE INTERMEDIATE RADICAL CATIONS

The one electron oxidations of benzyl phenyl ether (1), 2-phenylethyl phenyl ether (2) and 2-(4-methoxyphenyl)ethyl phenyl ether (3) promoted (a) by cerium(IV) ammonium nitrate (CAN) in AcOH, (b) electrochemically in AcOH-MeCN/AcOK and (c) photochemically in MeCN, in the presence of 9,10-dicyanoanthracene (DCA), have been investigated.With 1 benzaldehyde forms, under all the reaction conditions, accompanied by products of acetoxylation at the phenoxy ring (conditions a and b) or by phenyl benzoate (condition c).The CAN-promoted and the electochemical oxidation of 2 exclusively lead to substitution at the phenoxy ring, whereas only side-chain attack at the benzylic carbon occurs in all of the reactions of 3, with formation of 4-methoxybenzaldehyde and products of side-chain oxidation.Phenyl 4-methoxybenzoate is also formed (conditions b and c).However, when the electrochemical oxidation is carried out in the absence of AcOK, only a product of intermolecular ring closure forms.These results allow one to draw some interesting conclusion on the competition between the various reaction pathways available to the cation radicals which are the first formed reaction intermediates in these one electron processes.