1273000-93-3Relevant articles and documents
Dehydrogenative [4 + 2] cycloaddition of formamides with alkynes through double c-h activation
Nakao, Yoshiaki,Morita, Eiji,Idei, Hiroaki,Hiyama, Tamejiro
, p. 3264 - 3267 (2011)
Formamides having 1-arylalkyl groups on nitrogen undergo an unprecedented dehydrogenative [4 + 2] cycloaddition reaction with alkynes via nickel/AlMe 3 cooperative catalysis to give highly substituted dihydropyridone derivatives in good yields. Notably, the transformation proceeds through double functionalization of C(sp2)-H and C(sp3)-H bonds in the formamides.