1273019-39-8

Upstream product

• 1273019-35-4 (S)-1-((4R,6S)-2,2-dimethyl-6-(2-methylbut-3-en-2-yl)-1,3-dioxan-4-yl)butan-2-ol 
• 1273019-34-3 (S)-1-((4R,6S)-2,2-dimethyl-6-(2-methylbut-3-en-2-yl)-1,3-dioxan-4-yl)butan-2-yl propionate 
• 1273019-40-1 (3S,5S,7R)-5,7-dihydroxy-8,8-dimethyldec-9-en-3-yl propionate 
• 1273019-30-9 (3S,5S,7S)-5,7-dihydroxy-8,8-dimethyldec-9-en-3-yl propionate 
• 1273019-31-0 (3S,5S)-5-hydroxyoct-7-en-3-yl propionate 
• 1273019-33-2 (S)-6-hydroxyoct-1-en-4-one 
• 1273019-32-1 (S)-1-(2-allyl-1,3-dithian-2-yl)butan-2-ol 
• 1273019-38-7 methyl 2-((2S,6R)-6-((R)-2-(4-methoxyphenoxy)butyl)-tetrahydro-3,3-dimethyl-4-oxo-2H-pyran-2-yl)acetate 
• 1273019-41-2 methyl 2-((2S,4R,6S)-6-((R)-2-(4-methoxyphenoxy)butyl)-tetrahydro-4-hydroxy-3,3-dimethyl-2H-pyran-2-yl)acetate 
• 870096-05-2 (2S,3R,4S,5R)-3,4,5-trimethoxy-2-(phenylthio)tetrahydro-2H-pyran 
• 1273019-29-6 methyl 2-((2S,4S,6S)-6-((R)-2-(4-methoxyphenoxy)butyl)-tetrahydro-4-hydroxy-3,3-dimethyl-2H-pyran-2-yl)acetate 

Relevant academic research and scientific papers

Total synthesis of cyanolide A

The total synthesis of cyanolide A has been achieved in 14 steps from commercially available (S)-2-ethyloxirane, exploiting the palladium-catalyzed intramolecular alkoxycarbonylation as the key step to construct the tetrasubstituted cis-tetrahydropyran ring with high stereoselectivity.