1273142-85-0

Basic information

• Product Name: (E)-2-(4-(4-(pyridin-2-ylmethyl)piperazin-1-yl)styryl)-5-methylterephthalonitrile
• CAS NO: 1273142-85-0
• Molecular Weight: 419.529
• Mol File: 1273142-85-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-2-(4-(4-(pyridin-2-ylmethyl)piperazin-1-yl)styryl)-5-methylterephthalonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-(4-(pyridin-2-ylmethyl)piperazin-1-yl)styryl)-5-methylterephthalonitrile(1273142-85-0)
• EPA Substance Registry System: (E)-2-(4-(4-(pyridin-2-ylmethyl)piperazin-1-yl)styryl)-5-methylterephthalonitrile(1273142-85-0)

Safety Data

• Hazardous Substances Data: 1273142-85-0(Hazardous Substances Data)

Upstream product

• 120-07-0 2,2'-(phenylimino)bis[ethanol] 
• 1074-24-4 2,5-dibromo-p-xylene 
• 39095-25-5 2,5-dimethylbenzene-1,4-dicarbonitrile 
• 106-42-3 para-xylene 
• 952234-25-2 1-(diethyl phosphorylmethyl)-4-methyl-2,5-dicyanobenzene 
• 1208-03-3 4-(bis(2-chloroethyl)amino)benzaldehyde 
• 952234-24-1 2-(bromomethyl)-5-methylterephthalonitrile 
• 3731-51-9 2-(Aminomethyl)pyridine 
• 1198178-31-2 2-(2-{4-[bis(2-chloroethyl)amino]phenyl}vinyl)-5-methylterephthalonitrile 

Relevant articles and documents

Dicyanostilbene-derived two-photon fluorescence probe for free zinc ions in live cells and tissues with a large two-photon action cross section

A novel two-photon fluorescence probe for Zn2+ derived from dicyanostilbene as a two-photon fluorophore and 4-(pyridine-2-ylmethyl) piperazine as a novel Zn2+ ligand was developed. The probe shows a 72.5-fold fluorescence enhancement in response to Zn2+, a large two-photon action cross-section (580 GM), a noncytotoxic effect, and pH insensitivity in the biologically relevant range, and its dissociation constant (KdTP) is 0.52 ± 0.01 μM. The probe can selectively detect free Zn2+ ions in live cells for 1500 s or so and in living tissues at a depth of 80-150 μm without interference from other metal ions and the membrane-bound probes.