952234-25-2Relevant articles and documents
Double-cyano stilbene ethylene two-photon fluorescent solvent chromophore water-soluble probe and its synthetic method and application (by machine translation)
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Paragraph 0037-0041, (2018/10/19)
The invention belongs to the technical field of fine chemicals, in particular to double-cyano stilbene ethylene two-photon fluorescent solvent chromophore water-soluble probe and its synthetic method and application, the probe in order to double-cyano stilbene (DCS) for the two-photon fluorescent matrix preparation. The probe molecules of small size, good solubility in water and is suitable for solvent polarity detection, in addition to the fluorescence intensity of the probe, two-photon absorption cross section of the insured with viscosity changes obviously, display a very wide range of solvent chromophore, large two-photon absorption cross section and ultra-large Stokes displacement, thereby greatly improving the detection sensitivity, imaging resolution, sensitivity and transverse and longitudinal resolution, and the accuracy of the test; cell microscopic imaging experiment to demonstrate that its in a cell or tissue has good color range and absorption effect, can be very good detection and reflect cell change in viscosity of the situation, and itself not toxic to the cells. In biological, in the medical field has great application value. (by machine translation)
Double-photon fluorescent probe used for temperature detection and derived from carbazole and preparation method of double-photon fluorescent probe
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Paragraph 0032, (2018/04/03)
The invention relates to the technical field of temperature probes, in particular to a double-photon fluorescent probe used for temperature detection and derived from carbazole and a preparation method of the double-photon fluorescent probe. The structural formula of the double-photon fluorescent probe is shown in the description. The fluorescence quantum yield of the probe is high, the detectionrange is wide, the application range of the double-photon fluorescent probe is greatly widened, and the detection reliability is improved.
Dicyanostilbene-derived two-photon fluorescence probe for free zinc ions in live cells and tissues with a large two-photon action cross section
Huang, Chibao,Qu, Junle,Qi, Jing,Yan, Meng,Xu, Gaixia
scheme or table, p. 1462 - 1465 (2011/06/21)
A novel two-photon fluorescence probe for Zn2+ derived from dicyanostilbene as a two-photon fluorophore and 4-(pyridine-2-ylmethyl) piperazine as a novel Zn2+ ligand was developed. The probe shows a 72.5-fold fluorescence enhancement in response to Zn2+, a large two-photon action cross-section (580 GM), a noncytotoxic effect, and pH insensitivity in the biologically relevant range, and its dissociation constant (KdTP) is 0.52 ± 0.01 μM. The probe can selectively detect free Zn2+ ions in live cells for 1500 s or so and in living tissues at a depth of 80-150 μm without interference from other metal ions and the membrane-bound probes.